SCHEMBL7023893

SCHEMBL7023893

CC(C)c1nnc(N)n(N)c1=O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7029949 0.98 POLB (0.33) POLBGAA
SCHEMBL7025216 0.81 POLB (0.31) POLB
SCHEMBL11719711 0.78 POLB (0.33) POLB
SCHEMBL11722300 0.78 POLB (0.33) POLB
SCHEMBL11718225 0.75 POLB (0.32) POLB
SCHEMBL11716370 0.75 ALDH1A1 (0.42) POLB
SCHEMBL11717637 0.75 POLB (0.32) POLB
SCHEMBL11716645 0.73 POLB (0.67) POLBGAA
SCHEMBL11718619 0.73 ALDH1A1 (0.41) POLB
SCHEMBL7029971 0.71 ALDH1A1 (0.55) POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0889884-B1 1,2,4-TRIAZINE DERIVATIVES FOR THE INHIBITION OF PROTEIN GLYCOSYLATION ALTEON INC (US) 2003-01-29 EP disclosed
US-6380192-B1 FOR INHIBITING NONENZYMATIC CROSS-LINKING (PROTEIN AGING) ALTEON, INC. 2002-04-30 US disclosed
US-6060470-A Triazine compounds and methods of use therefor ALTEON, INC. 2000-05-09 US disclosed
US-5932578-A CAPABLE OF INHIBITING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS OF TARGET PROTEINS. FOOD SPOILAGE AND ANIMAL PROTEIN AGING CAN BE TREATED. ALTEON INC. (US) 1999-08-03 US disclosed
EP-0889884-A1 1,2,4-TRIAZINE DERIVATIVES FOR THE INHIBITION OF PROTEIN GLYCOSYLATION ALTEON, INC. (US) 1999-01-13 EP disclosed
WO-1997035849-A1 1,2,4-TRIAZINE DERIVATIVES FOR THE INHIBITION OF PROTEIN GLYCOSYLATION ALTEON INC. (US) 1997-10-02 WO disclosed