Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024898 | 0.86 | MAOB (0.68) | MAOBGSK3BBACE1ALKBH1ALDH1A1 | |
| SCHEMBL1283762 | 0.84 | CACNA1C (0.59) | CACNA1CMAOBGSK3BBACE1ALKBH1 | |
| SCHEMBL2554194 | 0.83 | CACNA1C (0.49) | CACNA1CMAOBGSK3BBACE1ALKBH1 | |
| SCHEMBL14762631 | 0.81 | CACNA1C (0.50) | CACNA1CMAOBGSK3BBACE1ALKBH1 | |
| SCHEMBL2088042 | 0.81 | MAOB (0.79) | CACNA1CMAOBALKBH1ALDH1A1GAA | |
| SCHEMBL1282619 | 0.81 | CACNA1C (0.49) | CACNA1CMAOBGSK3BBACE1ALKBH1 | |
| SCHEMBL21340748 | 0.80 | CACNA1C (0.52) | CACNA1CMAOBGSK3BBACE1ALKBH1 | |
| SCHEMBL17508221 | 0.80 | ALDH1A1 (0.53) | CACNA1CMAOBGSK3BBACE1ALKBH1 | |
| SCHEMBL811162 | 0.79 | CACNA1C (0.51) | CACNA1CMAOBALKBH1ALDH1A1LMNA | |
| SCHEMBL3625841 | 0.78 | MAOB (0.67) | MAOBALDH1A1GAALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1127476-C | 2-phenoxyaniline derivs. | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-11-12 | — | — | CN | disclosed |
| EP-1031556-B1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6162832-A | 2-Phenoxyaniline derivatives | TAISHO PHARMACEUTICAL CO., INC. (JP) | 2000-12-19 | — | — | US | disclosed |
| CN-1276783-A | 2-Phenoxyaniline Derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2000-12-13 | — | — | CN | disclosed |
| EP-1031556-A1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2000-08-30 | — | — | EP | disclosed |