Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.53 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.53 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.52 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024396 | 1.00 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL7357107 | 0.95 | ABCC9 (0.56) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL7357111 | 0.95 | ABCC9 (0.56) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL7023779 | 0.93 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL7023780 | 0.93 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL7022283 | 0.92 | NLRP3 (0.55) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL7022279 | 0.92 | NLRP3 (0.55) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL7023489 | 0.91 | NLRP3 (0.56) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL7023486 | 0.91 | NLRP3 (0.56) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL7017020 | 0.91 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11NLRP3DNMT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100775-B1 | 2,5-SUBSTITUTED BENZOLSULFONYLUREAS AND THIOUREAS, METHODS FOR THE PRODUCTION THEREOF, USE THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | AVENTIS PHARMA GMBH (DE) | 2003-12-17 | — | — | EP | disclosed |
| US-6410573-B1 | CARDIOVASCULAR DISEASES; POTASSIUM CHANNEL MODULATOR | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-06-25 | — | — | US | disclosed |
| EP-1100775-A2 | 2,5-SUBSTITUTED BENZOLSULFONYLUREAS AND THIOUREAS, METHODS FOR THE PRODUCTION THEREOF, USE THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | Hoechst Marion Roussel Deutschland GmbH (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000003978-A2 | 2,5-SUBSTITUTED BENZOLSULFONYLUREAS AND THIOUREAS, METHODS FOR THE PRODUCTION THEREOF, USE THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-01-27 | — | — | WO | disclosed |