Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7727868 | 0.85 | PKM (0.70) | PKMTHRBHTTMAPTATM | |
| SCHEMBL866120 | 0.84 | PKM (0.68) | PKMTHRBHTTMAPTATM | |
| SCHEMBL7025943 | 0.83 | PKM (0.66) | PKMTHRBHTTMAPTATM | |
| SCHEMBL14593304 | 0.81 | PKM (0.79) | PKMTHRBHTTMAPTATM | |
| SCHEMBL14503012 | 0.81 | PKM (0.78) | PKMTHRBHTTMAPTATM | |
| SCHEMBL8499870 | 0.78 | PKM (0.79) | PKMTHRBHTTMAPTATM | |
| SCHEMBL10207139 | 0.77 | PKM (0.58) | PKMTHRBHTTMAPTATM | |
| SCHEMBL12064248 | 0.77 | PKM (0.75) | PKMTHRBHTTMAPTATM | |
| SCHEMBL11409261 | 0.77 | PKM (0.72) | PKMTHRBHTTMAPTATM | |
| SCHEMBL19532853 | 0.77 | PKM (0.72) | PKMTHRBHTTMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276712-A2 | 2,6-DIAMINO-6-METHYL-HEPTANOIC ACID AND DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF | Degussa AG (DE) | 2003-01-22 | — | — | EP | disclosed |
| US-6504047-B2 | 2,6-diamino-6-methyl-heptanoic acid and derivatives as chemical intermediates useful for preperation of biological active compounds such as alpha-amino-epsilon caprolactam derivatives | DEGUSSA AG (DE) | 2003-01-07 | — | — | US | disclosed |
| US-20020016366-A1 | 2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparation thereof and use thereof | DEGUSSA AG (DE) | 2002-02-07 | — | — | US | disclosed |
| WO-2001083423-A2 | 2,6-DIAMINO-6-METHYL-HEPTANOIC ACID AND DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF | DEGUSSA AG (DE) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016366-A1 | 2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparation thereof and use thereof | CYP2D6, CYP2B6, CYP2A6 | PKM 1138/4885THRB 3751/4885HTT 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.