Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.66 |
| ▸ | THRB | P10828 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7727868 | 0.84 | PKM (0.70) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL8499709 | 0.84 | PKM (0.62) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL7024490 | 0.83 | PKM (0.68) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL866120 | 0.83 | PKM (0.68) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL8499460 | 0.81 | ATM (0.81) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL8499459 | 0.81 | ATM (0.81) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL14593304 | 0.80 | PKM (0.79) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL8498780 | 0.80 | ATM (0.83) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL8498782 | 0.80 | ATM (0.83) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL14503012 | 0.79 | PKM (0.78) | PKMTHRBHTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276712-A2 | 2,6-DIAMINO-6-METHYL-HEPTANOIC ACID AND DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF | Degussa AG (DE) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001083423-A2 | 2,6-DIAMINO-6-METHYL-HEPTANOIC ACID AND DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF | DEGUSSA AG (DE) | 2001-11-08 | — | — | WO | disclosed |