Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.59 |
| ▸ | PPARA | Q07869 | 14/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483502 | 0.94 | PPARG (0.65) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6486575 | 0.88 | PPARG (0.65) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6477333 | 0.86 | PPARG (0.78) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6475313 | 0.84 | PPARG (0.62) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6477724 | 0.83 | PPARG (0.63) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6488809 | 0.82 | PPARG (0.62) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6488201 | 0.82 | PPARG (0.74) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6487231 | 0.81 | PPARG (0.58) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6487342 | 0.81 | PPARG (0.58) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6485044 | 0.79 | PPARG (0.55) | PPARGPPARANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252150-B1 | HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2003-06-04 | — | — | EP | disclosed |