SCHEMBL7024939

C[SiH](C)[C@@]1(n2ccc(NC(=O)c3ccccc3)nc2=O)O[C@H](COC(C)(C)C)[C@@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	POLB	P06746	2/20	0.44

▸	P2RY6	Q15077	2/20	0.40

▸	P2RY14	Q15391	2/20	0.40

▸	NT5E	P21589	1/20	0.40

▸	ABL1	P00519	1/20	0.39

▸	RIN1	Q13671	1/20	0.39

▸	MEN1	O00255	2/20	0.33

▸	KMT2A	Q03164	2/20	0.33

▸	USP2	O75604	1/20	0.33

▸	MAPT	P10636	1/20	0.32

▸	NPC1	O15118	1/20	0.31

▸	LMNA	P02545	1/20	0.31

▸	RAB9A	P51151	1/20	0.31

▸	SMN1; SMN2	Q16637	1/20	0.31

▸	ALDH1A1	P00352	1/20	0.31

▸	HTT	P42858	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25400566	0.77	POLB (0.39)	POLBMEN1KMT2AUSP2MAPT
SCHEMBL6761673	0.72	POLA1 (0.31)	—
SCHEMBL8532580	0.71	FLT4 (0.32)	NT5E
SCHEMBL14929129	0.71	POLB (0.54)	POLBP2RY6P2RY14NT5EABL1
SCHEMBL14946265	0.71	POLB (0.54)	POLBP2RY6P2RY14NT5EABL1
SCHEMBL28294844	0.71	LMNA (0.34)	P2RY6P2RY14LMNA
SCHEMBL6761620	0.70	CD69 (0.31)	—
SCHEMBL28293053	0.70	—	—
SCHEMBL11027700	0.69	F2 (0.35)	POLBP2RY6P2RY14NT5EABL1
SCHEMBL6396743	0.69	MAPT (0.36)	POLBP2RY6P2RY14NT5EABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6518418-B1	Nucleotide sugars	THE SCRIPPS RESEARCH INSTITUTE	2003-02-11	—	—	US	disclosed