Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | ST6GAL1 | P15907 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.30 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293053 | 0.86 | — | — | |
| SCHEMBL28294920 | 0.85 | L3MBTL1 (0.36) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL28294841 | 0.81 | LMNA (0.33) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL6761673 | 0.76 | POLA1 (0.31) | POLA1 | |
| SCHEMBL17223095 | 0.75 | TYMP (0.41) | — | |
| SCHEMBL25390814 | 0.75 | PDE4D (0.38) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL7776536 | 0.74 | LMNA (0.44) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL10613710 | 0.73 | PDE3A (0.36) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL9182112 | 0.71 | PDE4D (0.31) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL7024939 | 0.71 | POLB (0.44) | LMNAP2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661232-A | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | 纽约哥伦比亚大学董事会 | 2019-04-19 | — | — | CN | disclosed |