Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 11/20 | 0.47 |
| ▸ | F2 | P00734 | 9/20 | 0.43 |
| ▸ | F7 | P08709 | 8/20 | 0.43 |
| ▸ | F3 | P13726 | 8/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7026586 | 0.91 | TPSAB1 (0.50) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7025534 | 0.88 | TPSAB1 (0.49) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7021593 | 0.83 | TPSAB1 (0.53) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7020338 | 0.81 | TPSAB1 (0.56) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL3247707 | 0.81 | F2 (0.60) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7020450 | 0.81 | TPSAB1 (0.54) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7024770 | 0.80 | TPSAB1 (0.50) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7449497 | 0.80 | TPSAB1 (0.57) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7019033 | 0.79 | TPSAB1 (0.47) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7019035 | 0.79 | TPSAB1 (0.47) | TPSAB1F2F7F3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |