Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 10/20 | 0.50 |
| ▸ | F2 | P00734 | 6/20 | 0.46 |
| ▸ | F7 | P08709 | 5/20 | 0.46 |
| ▸ | F3 | P13726 | 5/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025534 | 0.91 | TPSAB1 (0.49) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7019035 | 0.84 | TPSAB1 (0.47) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7019033 | 0.84 | TPSAB1 (0.47) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7026586 | 0.82 | TPSAB1 (0.50) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7449497 | 0.81 | TPSAB1 (0.57) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7025014 | 0.80 | TPSAB1 (0.47) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7020450 | 0.80 | TPSAB1 (0.54) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7021593 | 0.79 | TPSAB1 (0.53) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL5885589 | 0.79 | F2 (0.59) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7307429 | 0.78 | TPSAB1 (0.45) | TPSAB1F2F7F3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |