⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28714 | 0.78 | — | — | |
| SCHEMBL69481 | 0.78 | — | — | |
| SCHEMBL10423056 | 0.78 | — | — | |
| SCHEMBL1145630 | 0.78 | — | — | |
| Orcinol SCHEMBL68497 | 0.78 | — | — | |
| SCHEMBL11574035 | 0.78 | ALDH1A1 (1.00) | — | |
| SCHEMBL83549 | 0.78 | — | — | |
| SCHEMBL7139544 | 0.76 | ALDH1A1 (0.44) | — | |
| Orcinol SCHEMBL236740 | 0.76 | ALDH1A1 (0.80) | — | |
| Orcinol SCHEMBL11445808 | 0.76 | ALDH1A1 (0.80) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858840-A1 | INDOLE MACROCYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020221272-A1 | INDOLE MACROCYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2020-11-05 | — | — | WO | disclosed |
| US-8927779-B2 | Method for the hydroxylation of halogenated aryl compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-01-06 | — | — | US | disclosed |
| EP-2479203-A1 | AROMATIC POLYESTER | Muroran Institute of Technology (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120172570-A1 | AROMATIC POLYESTER | NITTA CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-20120157704-A1 | Method for the Hydroxylation of Halogenated Aryl Compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2012-06-21 | — | — | US | disclosed |
| US-8129493-B2 | Aromatic polyester | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2011-09-15 | — | — | US | disclosed |
| US-20110092662-A1 | AROMATIC POLYESTER | NITTA CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| US-4163112-A | INSECTICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1979-07-31 | — | — | US | disclosed |