Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.59 |
| ▸ | MAOB | P27338 | 5/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | SDHA | P31040 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CALML3 | P27482 | 1/20 | 0.59 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396646 | 0.88 | MAOA (0.72) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6396641 | 0.88 | MAOA (0.72) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6765396 | 0.85 | CALML3 (0.49) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8011270 | 0.84 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8011273 | 0.84 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6396624 | 0.84 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6396630 | 0.84 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7691880 | 0.84 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7103520 | 0.84 | MAOA (0.55) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7691878 | 0.84 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638955-B2 | Antibiotic oxazolidinone derivatives | SYNGENTA LIMITED (GB) | 2003-10-28 | — | — | US | disclosed |
| US-6365751-B1 | ACTIVE AGAINST GRAM-POSITIVE BACTERIA, IN PARTICULAR, AGAINST STRAINS RESISTANT TO VANCOMYCIN, AMINOGLYCOSIDES AND PENCILLINS AND DERIVATIVES; NONTOXIC | ZENECA LTD. (GB) | 2002-04-02 | — | — | US | disclosed |
| US-6271383-B1 | USEFUL ACTIVITY AGAINST GRAM-POSITIVE PATHOGENS; IN PARTICULAR, AGAINST VARIOUS STRAINS EXHIBITING RESISTANCE TO VANCOMYCIN AND AGAINST E. FAECIUM STRAINS RESISTANT TO BOTH AMINOGLYCOSIDES AND CLINICALLY USED BETA-LACTAMS. | ZENECA LIMITED (GB) | 2001-08-07 | — | — | US | disclosed |
| US-5981528-A | Antibiotic oxazolidinone derivatives | ZENECA LIMITED | 1999-11-09 | — | — | US | disclosed |