SCHEMBL7025815

SCHEMBL7025815

CCC/C=C/C1CCC(C2CCC(c3ccc(CCCO)c(F)c3)CC2)CC1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.34
SPHK1 Q9NYA1 1/20 0.31
PANK3 Q9H999 1/20 0.30
CTSK P43235 1/20 0.30
CTSC P53634 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7033122 0.94 PANK3 (0.31) PANK3CTSKCTSC
SCHEMBL7026539 0.91 CA2 (0.36) CA2PANK3CTSKCTSC
SCHEMBL7031726 0.86
SCHEMBL7031744 0.85 ESR2 (0.35) PANK3
SCHEMBL7028647 0.84 PANK3 (0.32) PANK3CTSKCTSC
SCHEMBL9480546 0.83 USP5 (0.33)
SCHEMBL9250475 0.83 USP5 (0.33)
SCHEMBL9250481 0.83 USP5 (0.33)
SCHEMBL9250486 0.83 USP5 (0.33)
SCHEMBL8390265 0.83 KDM5A (0.33) CTSKCTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0754668-B1 Fluorobenzylether derivatives ROLIC AG (CH) 2003-02-05 EP disclosed
EP-0754668-A2 Fluorobenzylether derivatives Rolic AG (CH) 1997-01-22 EP disclosed