Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686922 | 0.92 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAOBTUBB1ERN1 | |
| SCHEMBL13647524 | 0.84 | TDP1 (0.41) | ALDH1A1L3MBTL1MAOBTSHRTDP1 | |
| SCHEMBL9133798 | 0.82 | MAPT (0.39) | ALDH1A1MEN1MAPTHPGDMAPK1 | |
| SCHEMBL9133796 | 0.82 | MAPT (0.39) | ALDH1A1MEN1MAPTHPGDMAPK1 | |
| SCHEMBL14404466 | 0.80 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1MAOBTUBB1ERN1 | |
| SCHEMBL4059477 | 0.79 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MAOBTUBB1ERN1 | |
| SCHEMBL20892596 | 0.79 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MAOBTUBB1ERN1 | |
| SCHEMBL702232 | 0.78 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1MAOBTUBB1ERN1 | |
| SCHEMBL9009618 | 0.76 | KDM4E (0.44) | ALDH1A1L3MBTL1TUBB1KDM4ERAB9A | |
| SCHEMBL13683800 | 0.76 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAOBTUBB1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576974-B1 | Benzyliden-quinuclidinones as sunscreen agents | MERCK PATENT GMBH (DE) | 2003-02-05 | — | — | EP | disclosed |