Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034477 | 0.85 | MAPT (0.47) | MAPTKDM4ELMNAPOLBTP53 | |
| SCHEMBL7029160 | 0.85 | PRKCI (0.38) | MAPTLMNAPOLBTP53 | |
| SCHEMBL7032177 | 0.84 | KDM4E (0.47) | MAPTKDM4EKMT2ALMNATP53 | |
| SCHEMBL7028123 | 0.84 | KDM4E (0.39) | MAPTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL7033516 | 0.84 | KDM4E (0.42) | MAPTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL7031921 | 0.83 | POLB (0.41) | MAPTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL7029041 | 0.82 | KDM4E (0.44) | MAPTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL7031240 | 0.82 | KDM4E (0.44) | MAPTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL7031824 | 0.82 | LMNA (0.46) | MAPTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL7034000 | 0.81 | KDM4E (0.43) | MAPTKDM4EKMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162979-A1 | Substituted sulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-08-28 | — | — | US | disclosed |
| US-6441195-B1 | 2-ALKOXYCARBONYL-3-SULPHONAMIDE, SULPHONYL ISOCYANATE OR SULPHONYL ISOTHIOCYANATE-THIOPHENES; PRE- OR POSTEMERGENCE HERBICIDES; EFFICIENCY | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-27 | — | — | US | disclosed |
| US-6180567-B1 | REACTING 2-ALKOXYCARBONYL-BENZENESULFONAMIDE DERIVATIVE WITH 1,2,4-(1H)TRIAZOLE-5-(THI)ONE DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162979-A1 | Substituted sulphonylamino(thio)carbonyl compounds | CBR3, CTH, CBR1 | MAPT 4635/4885KDM4E 2583/4885KMT2A 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.