SCHEMBL7026451

SCHEMBL7026451

O[C](CF)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21929747 0.69
SCHEMBL4510148 0.67
SCHEMBL15990769 0.67
SCHEMBL6591708 0.65
Trifluoroacetic Acid SCHEMBL5701461 0.65 ACLY (0.40)
SCHEMBL5371307 0.64
SCHEMBL27245 0.63
SCHEMBL3307699 0.61
Trifluoroacetic Acid SCHEMBL28235039 0.61 ALDH1A1 (0.38)
SCHEMBL891574 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102351918-A Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing said compounds, their use and process for their preparation BOEHRINGER INGELHEIM INT 2012-02-15 CN claimed
CN-101437807-A Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing said compounds, their use and process for their preparation BOEHRINGER INGELHEIM INT (DE) 2009-05-20 CN claimed
CN-101384576-A Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture BOEHRINGER INGELHEIM INT (DE) 2009-03-11 CN claimed
WO-2002021216-A9 POLYMERS AND PHOTORESIST COMPOSITIONS COMPRISING ELECTRONEGATIVE GROUPS SHIPLEY CO LLC (US) 2003-04-03 WO claimed
US-20020058199-A1 Novel polymers and photoresist compositions comprising electronegative groups SHIPLEY COMPANY, L.L.C. 2002-05-16 US claimed
CN-110475772-A Pyridine compounds BASF SE 2019-11-19 CN disclosed
CN-109476561-A Capsule comprising being used as the benzyl propargyl ether of nitrification inhibitor 巴斯夫欧洲公司 2019-03-15 CN disclosed
CN-102666491-A Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline VITAE PHARMACEUTICALS INC 2012-09-12 CN disclosed
CN-101137606-B Process for oxidation of organic compounds DAICEL CHEM 2012-07-25 CN disclosed
CN-102351918-A Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing said compounds, their use and process for their preparation BOEHRINGER INGELHEIM INT 2012-02-15 CN disclosed
CN-101437807-A Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing said compounds, their use and process for their preparation BOEHRINGER INGELHEIM INT (DE) 2009-05-20 CN disclosed
CN-101384576-A Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture BOEHRINGER INGELHEIM INT (DE) 2009-03-11 CN disclosed
CN-1157380-C Substituted polycyclic aryl and heteroaryl pyrymidinones useful as anticoagulants agents �ź㴫 2004-07-14 CN disclosed
CN-1153764-C Substituted benzylaminopiperidine compounds ������ҩ�����޹�˾ 2004-06-16 CN disclosed
CN-1152023-C Substituted polycyclic aryl and heteroaryl uracils as anticoagulative agents 法玛西雅公司 2004-06-02 CN disclosed
CN-1378534-A Substituted polycyclic aryl and heteroaryl pyridones for selective inhibition of the coagulation cascade PHARMACIA CO (US) 2002-11-06 CN disclosed
CN-1351593-A Substituted polycyclic aryl and heteroaryl pyrymidinones useful as anticoagulants agents PHARMACIA CO (US) 2002-05-29 CN disclosed
CN-1351594-A Substituted polycyclic aryl and heteroaryl uracils as anticoagulative agents PHARMACIA CORP (US) 2002-05-29 CN disclosed
CN-1351595-A Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade PHARMACIA CO (US) 2002-05-29 CN disclosed
CN-1193961-A Substituted benzylaminopiperidine compounds PFIZER (US) 1998-09-23 CN disclosed