Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 12/20 | 0.52 |
| ▸ | F2 | P00734 | 7/20 | 0.44 |
| ▸ | F7 | P08709 | 6/20 | 0.44 |
| ▸ | F3 | P13726 | 6/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027931 | 0.91 | TPSAB1 (0.52) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7021153 | 0.86 | F2 (0.46) | F2PRSS1 | |
| SCHEMBL7027598 | 0.82 | TPSAB1 (0.54) | TPSAB1F2F7F3PRSS1 | |
| Hydrochloric Acid SCHEMBL7022577 | 0.81 | TPSAB1 (0.53) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7020338 | 0.79 | TPSAB1 (0.56) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7027983 | 0.78 | F2 (0.56) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL3242830 | 0.77 | F2 (0.66) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7021593 | 0.74 | TPSAB1 (0.53) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7021053 | 0.73 | TPSAB1 (0.51) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7020341 | 0.73 | TPSAB1 (0.51) | TPSAB1F2F7F3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |