Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426123 | 0.86 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNACES2CES1 | |
| SCHEMBL7021730 | 0.83 | CA12 (0.49) | ALDH1A1SMN1; SMN2LMNACES2CES1 | |
| SCHEMBL7028909 | 0.79 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNACES2CES1 | |
| SCHEMBL5162688 | 0.78 | NAPRT (0.48) | ALDH1A1LMNAKMT2AMEN1HTT | |
| SCHEMBL9356312 | 0.77 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNACES2CES1 | |
| SCHEMBL10577256 | 0.76 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNACES2CES1 | |
| SCHEMBL585256 | 0.76 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNACES2CES1 | |
| SCHEMBL6890869 | 0.74 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNACES2CES1 | |
| SCHEMBL62897 | 0.74 | TDP1 (0.52) | ALDH1A1SMN1; SMN2LMNACES2CES1 | |
| SCHEMBL28679723 | 0.73 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346977-A1 | Method for producing aryl-aminopropanols | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | claimed |
| EP-1346977-A1 | Method for producing aryl-aminopropanols | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |