Sugi Predict

Sugi Predict / Compounds / SCHEMBL585256

SCHEMBL585256

SCHEMBL585256

Cc1ccc(C(=O)C(C)C)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.56
▸ LMNA P02545 3/20 0.56
▸ CES2 O00748 3/20 0.56
▸ CES1 P23141 3/20 0.56
▸ SMN1; SMN2 Q16637 4/20 0.54
▸ GAA P10253 2/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ DBH P09172 1/20 0.54
▸ RECQL P46063 1/20 0.54
▸ MEN1 O00255 3/20 0.50
▸ KMT2A Q03164 3/20 0.50
▸ PKM P14618 2/20 0.50
▸ HTT P42858 2/20 0.50
▸ ATM Q13315 2/20 0.50
▸ NPSR1 Q6W5P4 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ HPGD P15428 1/20 0.50
▸ NLRP1 Q9C000 1/20 0.50
▸ NTSR1 P30989 1/20 0.50
▸ CHRM2 P08172 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10121174 0.89 KDM4E (0.62) ALDH1A1LMNACES2CES1SMN1; SMN2
SCHEMBL10577256 0.85 ALDH1A1 (0.56) ALDH1A1LMNACES2CES1SMN1; SMN2
SCHEMBL6890869 0.83 ALDH1A1 (0.54) ALDH1A1LMNACES2CES1SMN1; SMN2
SCHEMBL2233657 0.82 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
SCHEMBL12418688 0.82 KDM4E (0.56) ALDH1A1LMNASMN1; SMN2GAAKDM4E
SCHEMBL10941943 0.82 KDM4E (0.56) ALDH1A1LMNASMN1; SMN2GAAKDM4E
SCHEMBL23682946 0.81 ALDH1A1 (0.52) ALDH1A1LMNACES2CES1SMN1; SMN2
SCHEMBL1702619 0.81 KDM4E (0.50) ALDH1A1LMNACES2CES1SMN1; SMN2
SCHEMBL19520246 0.81 ALDH1A1 (0.52) ALDH1A1LMNACES2CES1SMN1; SMN2
SCHEMBL10384383 0.81 ALDH1A1 (0.52) ALDH1A1LMNACES2CES1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104710256-A Cheap and efficient synthesis method of alpha-hydroxyketone compound UNIV BEIJING 2015-06-17 — — CN claimed
EP-2072083-B1 Utilisation of 2.4'-dimethyl-propiophenon as an aroma SYMRISE AG (DE) 2012-02-15 — — EP claimed
US-20100324090-A1 COMPOSITIONS OF TOLPERISONE Sanochemia Pharmazeutika GmbH (AT) 2010-12-23 — — US claimed
US-20090253743-A1 COMPOSITIONS OF TOLPERISONE AVIGEN, INC. (US) 2009-10-08 — — US claimed
US-20090162308-A1 USE OF 2,4'-DIMETHYLPROPIOPHENONE AS A FRAGRANCE SUBSTANCE SYMRISE GMBH & CO. KG (DE) 2009-06-25 — — US claimed
EP-2072083-A1 Utilisation of 2.4'-dimethyl-propiophenon as an aroma Symrise GmbH & Co. KG (DE) 2009-06-24 — — EP claimed
WO-2008133937-A2 COMPOSITIONS OF TOLPERISONE AVIGEN, INC. (US) 2008-11-06 — — WO claimed
CN-1249009-C Novel bifunctional photoinitiators CIBA SC HOLDING AG (CH) 2006-04-05 — — CN claimed
CN-1582267-A Novel bifunctional photoinitiators CIBA SC HOLDING AG (CH) 2005-02-16 — — CN claimed
US-20240207355-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG L-Base Co., Ltd. (KR) 2024-06-27 — — US disclosed
CN-114853586-B Preparation method of phenanthrene ketone derivative 扬州市职业大学(扬州开放大学) 2024-03-15 — — CN disclosed
US-20240024497-A1 METHODS FOR THE SYNTHESIS OF PROTEIN-DRUG CONJUGATES CIDARA THERAPEUTICS, INC. 2024-01-25 — — US disclosed
US-20230399515-A1 PHTHALOCYANINE DYE COMPOUNDS, CONJUGATES AND METHODS OF USE THEREOF Rakuten Medical, Inc. 2023-12-14 — — US disclosed
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-12-14 — — US disclosed
EP-0273647-A1 Coumaran derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1988-07-06 — — EP disclosed
US-4352748-A Novel acyl-polyalkylindan compounds and the use thereof as a base for perfume, as well as perfume compositions NAARDEN INTERNATIONAL N.V. (NL) 1982-10-05 — — US disclosed
US-RE30634-E INSECTICIDES SHELL OIL COMPANY (US) 1981-06-02 — — US disclosed
US-4182730-A Process for the preparation of substituted dihydrocinnamaldehydes via novel β-chlorocinnamaldehydes GIVAUDAN CORPORATION (US) 1980-01-08 — — US disclosed
US-4116665-A Method of regulating the growth of aquatic weeds with pyridine derivatives ELI LILLY AND COMPANY (US) 1978-09-26 — — US disclosed
US-4079149-A INSECTICIDES SHELL OIL COMPANY (US) 1978-03-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A ALDH1A1 3164/4885LMNA 3451/4885CES2 2044/4885
US-20090253743-A1 COMPOSITIONS OF TOLPERISONE ADAMTS4, MMP17, ADAMTS5 ALDH1A1 202/4885LMNA 3333/4885CES2 175/4885
US-20090162308-A1 USE OF 2,4'-DIMETHYLPROPIOPHENONE AS A FRAGRANCE SUBSTANCE CYP1B1, CYP4A22, ROS1 ALDH1A1 17/4885LMNA 4524/4885CES2 877/4885
US-20240024497-A1 METHODS FOR THE SYNTHESIS OF PROTEIN-DRUG CONJUGATES RNGTT, RNMT, DNPEP ALDH1A1 2284/4885LMNA 3860/4885CES2 258/4885
US-20100324090-A1 COMPOSITIONS OF TOLPERISONE ADAMTS4, MMP17, ADAMTS5 ALDH1A1 202/4885LMNA 3333/4885CES2 175/4885
US-20240207355-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG ALPG, SLC11A2, SGTA ALDH1A1 4761/4885LMNA 4762/4885CES2 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.