Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 20/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 15/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 15/20 | 0.49 |
| ▸ | GABRP | O00591 | 12/20 | 0.49 |
| ▸ | GABRD | O14764 | 12/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 12/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 12/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 12/20 | 0.49 |
| ▸ | GABRE | P78334 | 12/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 12/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 12/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 12/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 12/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2841648 | 0.89 | GABRB3 (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL2835106 | 0.89 | GABRB3 (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7673675 | 0.87 | GABRB3 (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL41972 | 0.87 | GABRP (0.59) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL2839803 | 0.85 | GABRB3 (0.44) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7025320 | 0.85 | GABRB3 (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL13134024 | 0.85 | GABRB3 (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL8545686 | 0.83 | GABRB3 (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL2835863 | 0.83 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL2492625 | 0.83 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638956-B2 | Pesticidal 1-arylpyrazoles | RHONE-POULENC, INC. | 2003-10-28 | — | — | US | disclosed |
| US-20030144251-A1 | Pesticidal 1-arylpyrazoles | RHONE-POULENC INC. | 2003-07-31 | — | — | US | disclosed |
| US-6500850-B2 | 1-ARYLPYRAZOLE OXIME DERIVATIVES; SAFE SYSTEMIC INSECTICIDES FOR CONTROL OF ARTHROPOD, NEMATODE, HELMINTH OR PROTOZOAN PESTS | RHONE-POULENC INC. | 2002-12-31 | — | — | US | disclosed |
| EP-0948485-B1 | PESTICIDAL 1-ARYLPYRAZOLES | AVENTIS CROPSCIENCE SA (FR) | 2002-09-25 | — | — | EP | disclosed |
| US-20020045758-A1 | Pesticidal 1-arylpyrazoles | RHONE-POULENC INC. | 2002-04-18 | — | — | US | disclosed |
| US-6350771-B1 | Pesticidal 1-arylpyrazoles | RHONE-POULENC, INC. | 2002-02-26 | — | — | US | disclosed |
| EP-0948485-A1 | PESTICIDAL 1-ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998028278-A1 | PESTICIDAL 1-ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1998-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045758-A1 | Pesticidal 1-arylpyrazoles | CYP1B1, CYP2E1, CYP1A1 | GABRB3 1485/4885GABRA2 2380/4885GABRB2 1699/4885 |
| US-20030144251-A1 | Pesticidal 1-arylpyrazoles | CYP1B1, CYP2E1, CYP1A1 | GABRB3 1485/4885GABRA2 2380/4885GABRB2 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.