SCHEMBL7027832

SCHEMBL7027832

C=C(F)c1ccccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 9/20 0.48
KDM4E B2RXH2 6/20 0.48
ALDH1A1 P00352 6/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
CA12 O43570 2/20 0.48
CA2 P00918 2/20 0.48
CA4 P22748 2/20 0.48
CA14 Q9ULX7 2/20 0.48
CA1 P00915 1/20 0.48
HMGB1 P09429 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
HSD17B10 Q99714 6/20 0.46
MAPT P10636 5/20 0.46
TSHR P16473 2/20 0.46
NPC1 O15118 4/20 0.45
LMNA P02545 4/20 0.45
ALOX15 P16050 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4801020 0.78 HPGD (0.52) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL17474473 0.78 HPGD (0.52) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL28252553 0.76 HPGD (0.50) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL3190837 0.76 HPGD (0.56) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL12856009 0.74 HPGD (0.48) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL12819640 0.74 HPGD (0.48) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL29349932 0.74 KMT2A (0.56) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL27516051 0.74 KMT2A (0.56) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL208880 0.74 KMT2A (0.56) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL7175383 0.74 ALDH1A1 (0.48) HPGDKDM4EALDH1A1SMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3031856-B1 CROSSLINKABLE FLUORINATED ELASTOMER COMPOSITION AND CROSSLINKED PRODUCT THEREOFa AGC INC (JP) 2019-07-10 EP disclosed
US-10066077-B2 Crosslinkable fluorinated elastomer composition and crosslinked product thereof ASAHI GLASS COMPANY, LIMITED (JP) 2018-09-04 US disclosed
EP-3031856-A1 FLUORINE-CONTAINING CROSSLINKABLE ELASTOMER COMPOSITION AND CROSSLINKED PRODUCT THEREOF Asahi Glass Company, Limited (JP) 2016-06-15 EP disclosed
US-20160137809-A1 CROSSLINKABLE FLUORINATED ELASTOMER COMPOSITION AND CROSSLINKED PRODUCT THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2016-05-19 US disclosed
WO-2002021216-A9 POLYMERS AND PHOTORESIST COMPOSITIONS COMPRISING ELECTRONEGATIVE GROUPS SHIPLEY CO LLC (US) 2003-04-03 WO disclosed
US-20020058199-A1 Novel polymers and photoresist compositions comprising electronegative groups SHIPLEY COMPANY, L.L.C. 2002-05-16 US disclosed
US-20020058198-A1 Fluorinated phenolic polymers and photoresist compositions comprising same SHIPLEY COMPANY, L.L.C. 2002-05-16 US disclosed
WO-2002021216-A2 POLYMERS AND PHOTORESIST COMPOSITIONS COMPRISING ELECTRONEGATIVE GROUPS SHIPLEY COMPANY, L.L.C. (US) 2002-03-14 WO disclosed
WO-2002021212-A2 FLUORINATED PHENOLIC POLYMERS AND PHOTORESIST COMPOSITIONS COMPRISING SAME SHIPLEY COMPANY, L.L.C. (US) 2002-03-14 WO disclosed