Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801020 | 0.78 | HPGD (0.52) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| SCHEMBL10736476 | 0.78 | HPGD (0.56) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| SCHEMBL12156371 | 0.77 | ALDH1A1 (0.60) | ALDH1A1HPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL27303906 | 0.77 | TRPA1 (0.54) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| SCHEMBL3190837 | 0.76 | HPGD (0.56) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| SCHEMBL28252553 | 0.76 | HPGD (0.50) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylamide SCHEMBL27340552 | 0.75 | KDM4E (0.79) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| SCHEMBL12856009 | 0.74 | HPGD (0.48) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| SCHEMBL7027832 | 0.74 | HPGD (0.48) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| SCHEMBL12819640 | 0.74 | HPGD (0.48) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2994463-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS | GALAPAGOS NV (BE) | 2017-10-25 | — | — | EP | disclosed |
| US-6576400-B1 | Acrylic ester polymer | TORAY INDUSTRIES, INC. (JP) | 2003-06-10 | — | — | US | disclosed |
| WO-2001066106-A1 | A PHARMACEUTICAL COMPOSITION HAVING CHLOROGENIC ACID AS ACTIVE COMPONENT FOR PREVENTING OR TREATING THE DECLINING OF MALE REPRODUCTION CAPABILITY | WOORICHEM TECH CO., LTD. (KR) | 2001-09-13 | — | — | WO | disclosed |
| EP-1031880-A1 | POSITIVE RADIATION-SENSITIVE COMPOSITION | TORAY INDUSTRIES, INC. (JP) | 2000-08-30 | — | — | EP | disclosed |