SCHEMBL702789

SCHEMBL702789

C=CCCCCOC(COCCCCCCCCCCCCCCCC)COC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 6/20 0.49
PLA2G10 O15496 3/20 0.49
PLA2G1B P04054 3/20 0.49
PLA2G5 P39877 3/20 0.49
LPAR1 Q92633 4/20 0.39
LPAR3 Q9UBY5 4/20 0.39
LPAR2 Q9HBW0 1/20 0.39
PLA2G2C Q5R387 1/20 0.37
TSHR P16473 1/20 0.36
TLR2 O60603 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1963642 1.00 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL2232582 1.00 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL2232632 1.00 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL2232437 1.00 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL2234605 1.00 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL2231918 1.00 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL2233038 0.98 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL25300207 0.95 PLA2G2A (0.43) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL2313261 0.94 PLA2G2A (0.45) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL8004697 0.91 PLA2G2A (0.51) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9968622-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2018-05-15 US disclosed
US-9968622-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2018-05-15 US disclosed
US-20170246197-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-08-31 US disclosed
US-20170246197-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-08-31 US disclosed
US-9566288-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-02-14 US disclosed
US-9566288-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-02-14 US disclosed
EP-2125838-B1 IMPROVED PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS VASCULAR BIOGENICS LTD (IL) 2016-05-11 EP disclosed
EP-2604614-B1 Oxidized phospholipids VASCULAR BIOGENICS LTD (IL) 2016-03-09 EP disclosed
US-9206206-B2 Oxidized lipid compounds and uses thereof VASCULAR BIOGENICS LTD. (IL) 2015-12-08 US disclosed
US-20150216882-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2015-08-06 US disclosed
US-20100317881-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS VASCULAR BIOGENICS LTD. (IL) 2010-12-16 US disclosed
CN-101891760-A Improving one's methods of preparation oxidized phospholipids VASCULAR BIOGENICS LTD 2010-11-24 CN disclosed
US-7807847-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2010-10-05 US disclosed
US-7807847-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2010-10-05 US disclosed
CN-101679463-A Improved process for preparing oxidized phospholipids VASCULAR BIOGENICS LTD 2010-03-24 CN disclosed
EP-2125838-A2 IMPROVED PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS Vascular Biogenics Ltd. (IL) 2009-12-02 EP disclosed
WO-2008084472-A2 IMPROVED PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS VASCULAR BIOGENICS LTD. (IL) 2008-07-17 WO disclosed
CN-101039680-A Improved process for preparing oxidized phospholipids VASCULAR BIOGENICS LTD (IL) 2007-09-19 CN disclosed
US-20070112211-A1 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2007-05-17 US disclosed
US-20070112211-A1 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317881-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS PHOSPHO1, SGMS1, SGMS2 PLA2G2A 47/4885PLA2G10 52/4885PLA2G1B 26/4885
US-20150216882-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 PLA2G2A 48/4885PLA2G10 45/4885PLA2G1B 43/4885
US-20170246197-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 PLA2G2A 48/4885PLA2G10 45/4885PLA2G1B 43/4885
US-20070112211-A1 Process for the preparation of oxidized phospholipids PHOSPHO1, SGMS1, SGMS2 PLA2G2A 47/4885PLA2G10 52/4885PLA2G1B 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.