⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2256300 | 0.95 | — | — | |
| Fluoride SCHEMBL3216899 | 0.95 | — | — | |
| SCHEMBL908136 | 0.95 | — | — | |
| SCHEMBL2253031 | 0.95 | — | — | |
| Fluoride SCHEMBL11270216 | 0.95 | ALDH1A1 (0.32) | — | |
| Fluoride SCHEMBL7557874 | 0.91 | CA1 (0.33) | — | |
| Fluoride SCHEMBL7557871 | 0.91 | CA1 (0.33) | — | |
| SCHEMBL1258053 | 0.84 | — | — | |
| SCHEMBL1870030 | 0.84 | — | — | |
| SCHEMBL1843941 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004669-A1 | AZAHETEROCYCLYL DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2008-12-24 | — | — | EP | claimed |
| WO-2007118830-A1 | AZAHETEROCYCLYL DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-10-25 | — | — | WO | claimed |
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | claimed |
| EP-1251133-B1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2004-10-13 | — | — | EP | claimed |
| US-6680313-B2 | 1-HYDROXYETHYL-2(IMIDAZO(5,1B)THIAZOL-2-YL-1-CARBAPEN-2-EM-3-C CARBOXYLIC ACID OR SALT, EXCELLENT ANTIBIOTIC ACTIVITY AGAINST A WIDE SPECTRUM OF BACTERIA | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-20 | — | — | US | claimed |
| US-20030027809-A1 | Novel carbapenum derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2003-02-06 | — | — | US | claimed |
| EP-1251133-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2002-10-23 | — | — | EP | claimed |
| US-4614819-A | REACTING A THIOL ESTER COMPOUND WITH 7-AMINOCEPHALOSPORIN IN PRESENCE OF BORON TRIFLUORIDE | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-09-30 | — | — | US | claimed |
| US-4438109-A | Tylosin derivatives | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1984-03-20 | — | — | US | claimed |
| EP-0004320-B1 | 1-SUBSTITUTED-THIOMETHYLTRIAZOLOBENZODIAZEPINES, PREPARATION THEREOF, THEIR USE, AND A PHARMACEUTICAL COMPOSITION | SHIONOGI & CO., LTD. (JP) | 1981-12-16 | — | — | EP | claimed |
| US-4073930-A | Carbamoyloximes and oximes and insecticidal and miticidal compositions and methods employing them | UNION CARBIDE CORPORATION (US) | 1978-02-14 | — | — | US | claimed |
| US-4071627-A | 2-Oximino-tetrahydro-1,4-thiazin-5-one compounds and pesticidal carbamate derivatives | UNION CARBIDE CORPORATION (US) | 1978-01-31 | — | — | US | claimed |
| JP-1026580-A | — | — | None | — | — | JP | disclosed |
| EP-4371979-A1 | FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT | Kumiai Chemical Industry Co., Ltd. (JP) | 2024-05-22 | — | — | EP | disclosed |
| CN-117693500-A | Carboxamide derivative and agricultural/horticultural plant disease control agent | 组合化学工业株式会社 | 2024-03-12 | — | — | CN | disclosed |
| US-20230089247-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | ZYDUS LIFESCIENCES LIMITED (IN) | 2023-03-23 | — | — | US | disclosed |
| EP-0004320-A1 | 1-Substituted-thiomethyltriazolobenzodiazepines, preparation thereof, their use, and a pharmaceutical composition | SHIONOGI & CO., LTD. (JP) | 1979-10-03 | — | — | EP | disclosed |
| US-4159984-A | METAL AND PROTON DONOR | SHIONOGI & CO., LTD. (JP) | 1979-07-03 | — | — | US | disclosed |
| US-4073930-A | Carbamoyloximes and oximes and insecticidal and miticidal compositions and methods employing them | UNION CARBIDE CORPORATION (US) | 1978-02-14 | — | — | US | disclosed |
| US-4071627-A | 2-Oximino-tetrahydro-1,4-thiazin-5-one compounds and pesticidal carbamate derivatives | UNION CARBIDE CORPORATION (US) | 1978-01-31 | — | — | US | disclosed |