⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL11270216 | 1.00 | ALDH1A1 (0.32) | — | |
| Fluoride SCHEMBL7557874 | 0.96 | CA1 (0.33) | — | |
| Fluoride SCHEMBL7557871 | 0.96 | CA1 (0.33) | — | |
| SCHEMBL702806 | 0.95 | — | — | |
| SCHEMBL2256300 | 0.91 | — | — | |
| SCHEMBL2253031 | 0.91 | — | — | |
| SCHEMBL1258053 | 0.80 | — | — | |
| SCHEMBL1870030 | 0.80 | — | — | |
| SCHEMBL1871136 | 0.67 | — | — | |
| Fluoride SCHEMBL526120 | 0.67 | MGLL (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056581-A1 | Substituted Piperidino Phenyloxazolidinones | PATEL MAHESH VITHALBHAI | 2010-03-04 | — | — | US | claimed |
| US-4284764-A | Process for the preparation of 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and novel 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy derivatives produced thereby | SCHERING CORPORATION (US) | 1981-08-18 | — | — | US | claimed |
| EP-2018792-B1 | SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES | WOCKHARDT LTD (IN) | 2015-09-16 | — | — | EP | disclosed |
| US-8217058-B2 | Substituted piperidino phenyloxazolidinones | WOCKHARDT LTD. (IN) | 2012-07-10 | — | — | US | disclosed |
| US-20100056581-A1 | Substituted Piperidino Phenyloxazolidinones | PATEL MAHESH VITHALBHAI | 2010-03-04 | — | — | US | disclosed |
| EP-2018792-A2 | SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES | Wockhardt Limited (IN) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007132314-A2 | SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES | WOCKHARDT LTD (IN) | 2007-11-22 | — | — | WO | disclosed |
| EP-0009227-B1 | FLUORINATION PROCESS AND FLUORO ANALOGS OF HYDROCODONE AND OXYCODONE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-01 | — | — | EP | disclosed |
| US-4284764-A | Process for the preparation of 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and novel 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy derivatives produced thereby | SCHERING CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |
| US-4246270-A | TRANQUILIZERS, MUSCLE RELAXANTS, AND SEDATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-20 | — | — | US | disclosed |
| US-4241065-A | Fluoro analogs of hydrocodone and oxycodone useful as analgesics, narcotic antagonists or both | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-12-23 | — | — | US | disclosed |
| US-4236008-A | MORPHINE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4212815-A | REACTING A KETONE WITH AN N,N-DISUBSTITUTED AMINOSULFUR TRIFLUORIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| EP-0009227-A1 | Fluorination process and fluoro analogs of hydrocodone and oxycodone | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-04-02 | — | — | EP | disclosed |
| US-4120856-A | REACTING 3-HYDROXY-BENZODIAZEPINES WITH AMINOSULFUR TRIFLUORIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
| US-3940402-A | POLYMERIZATION CATALYSTS | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1976-02-24 | — | — | US | disclosed |