Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12808900 | 0.88 | HRH1 (0.53) | SIGMAR1HRH1HRH3TDP1POLB | |
| SCHEMBL7775252 | 0.86 | HRH1 (0.56) | SIGMAR1HRH1HRH3TDP1POLB | |
| SCHEMBL7776781 | 0.84 | ALDH1A1 (0.48) | SIGMAR1HRH1HRH3POLB | |
| SCHEMBL7813558 | 0.83 | CYP2C19 (0.44) | — | |
| SCHEMBL7769118 | 0.83 | NPC1 (0.50) | SIGMAR1HRH1HRH3POLB | |
| SCHEMBL7775256 | 0.81 | HRH1 (0.56) | SIGMAR1HRH1HRH3TDP1POLB | |
| SCHEMBL7028228 | 0.80 | SIGMAR1 (0.46) | SIGMAR1HRH1HRH3TDP1 | |
| SCHEMBL7773290 | 0.80 | SIGMAR1 (0.49) | SIGMAR1HRH1HRH3TDP1 | |
| SCHEMBL9186876 | 0.77 | SIGMAR1 (0.46) | SIGMAR1HRH1HRH3TDP1POLB | |
| SCHEMBL7776766 | 0.75 | HRH1 (0.60) | SIGMAR1HRH1HRH3TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517325-B1 | Drug hapten analogues for immunoassays | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-10-31 | — | — | EP | claimed |
| US-5284948-A | Drug hapten analogues for immunoassays | EASTMAN KODAK COMPANY (US) | 1994-02-08 | — | — | US | claimed |
| EP-0687910-B1 | Test kit and method for competitive specific binding assay | JOHNSON & JOHNSON CLIN DIAG (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-0685740-B1 | Separation-free specific binding assays using anti-inhibitor antibodies | JOHNSON & JOHNSON CLIN DIAG (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-0517325-B1 | Drug hapten analogues for immunoassays | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0517326-B1 | Labeled drug hapten analogues for immunoassays | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0517327-B1 | Immunoassay with labeled hapten analogues | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0690071-B1 | Inhibitor and anti-inhibitor monoclonal antibodies specific for horseradish peroxidase | JOHNSON & JOHNSON CLIN DIAG (US) | 2000-12-27 | — | — | EP | disclosed |
| US-5916757-A | PROVIDES DIRECT CORRELATION OF GENERATED SIGNAL TO TARGET SPECIFIC BINDING LIGAND | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5776714-A | USED TO REMOVE THE BIAS CAUSED BY PRESENCE OF HEMOGLOBIN IN TEST SPECIMENS | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS INC. (US) | 1998-07-07 | — | — | US | disclosed |
| US-5650324-A | Inhibitor and anti-inhibitor monoclonal antibodies specific for horseradish peroxidase | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1997-07-22 | — | — | US | disclosed |
| US-5565326-A | ONE STEP CHEMICAL ANALYSIS BY RECEPTOR BINDING ASSAY | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0693552-A2 | Analytical element, composition and method using modified apo-horseradish peroxidase | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0690071-A2 | Inhibitor and anti-inhibitor monoclonal antibodies specific for horseradish peroxidase | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1996-01-03 | — | — | EP | disclosed |
| EP-0687910-A1 | Test kit and method for competitive specific binding assay | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1995-12-20 | — | — | EP | disclosed |
| EP-0685740-A2 | Separation-free specific binding assays using anti-inhibitor antibodies | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5298403-A | Having hydantoin or barbiturate nucleus | EASTMAN KODAK COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| US-5284948-A | Drug hapten analogues for immunoassays | EASTMAN KODAK COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0517326-A2 | Labeled drug hapten analogues for immunoassays | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-09 | — | — | EP | disclosed |
| EP-0517325-A2 | Drug hapten analogues for immunoassays | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-09 | — | — | EP | disclosed |