SCHEMBL7028828

SCHEMBL7028828

O=C(c1ccccc1CCCO)c1ccccc1CCCO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.46
DHODH Q02127 1/20 0.40
CNR2 P34972 3/20 0.40
ALDH1A1 P00352 3/20 0.40
CNR1 P21554 2/20 0.40
LMNA P02545 2/20 0.40
ADRB2 P07550 1/20 0.39
ELANE P08246 1/20 0.38
PTPN1 P18031 2/20 0.38
SLC16A3 O15427 4/20 0.38
HTT P42858 1/20 0.38
GAA P10253 2/20 0.37
HPGD P15428 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1062035 0.89 AKR1C3 (0.50) FOLH1ALDH1A1ELANEGAAL3MBTL1
SCHEMBL7618622 0.87 FOLH1 (0.48) FOLH1ALDH1A1LMNAADRB2PTPN1
SCHEMBL5806456 0.86 FOLH1 (0.63) FOLH1DHODHALDH1A1PTPN1SLC16A3
SCHEMBL10420414 0.84 LMNA (0.45) FOLH1DHODHALDH1A1LMNAADRB2
SCHEMBL2021481 0.84 BCAT2 (0.46) FOLH1DHODHALDH1A1LMNAGAA
SCHEMBL28882596 0.82 AKR1C3 (0.47) FOLH1DHODHALDH1A1ELANESLC16A3
SCHEMBL945386 0.82 AKR1C3 (0.47) FOLH1DHODHALDH1A1ELANESLC16A3
SCHEMBL17318743 0.82 AKR1C3 (0.47) FOLH1DHODHALDH1A1ELANESLC16A3
SCHEMBL1404026 0.82 TSHR (0.47) FOLH1CNR2ALDH1A1LMNAHTT
SCHEMBL14244547 0.82 FOLH1 (0.44) FOLH1ALDH1A1LMNAADRB2SLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933343-B1 Method for producing sized, coated ceramic fibers COI CERAMICS INC (US) 2003-06-25 EP claimed
US-6251520-B1 APPLYING NON-AQUEOUS SIZING TO CERAMIC FIBER; CURING DOW CORNING CORPORATION 2001-06-26 US claimed
EP-0933343-A1 Method for producing sized, coated ceramic fibers DOW CORNING CORPORATION (US) 1999-08-04 EP claimed
US-5358674-A Pyrolyzing a radiation exposed spun-bonded fiber from an or blends of modified polyalkylvinylsiloxanes and photoinitiators DOW CORNING CORPORATION (US) 1994-10-25 US claimed
US-5063102-A Ultraviolet, polymethylsiloxane, mercaptan curing agent, photoinitiator; protecting electronic devices against environment by coating or encapsulating with cured composition DOW CORNING CORPORATION (US) 1991-11-05 US claimed
US-12227650-B2 Method of preparing silicone-acrylate hybrid composition and hybrid composition formed thereby DOW GLOBAL TECHNOLOGIES LLC (US) 2025-02-18 US disclosed
US-11732135-B2 Photocurable silicone composition DOW SILICONES CORPORATION (US) 2023-08-22 US disclosed
US-11623989-B2 Photocurable silicone composition DOW SILICONES CORPORATION (US) 2023-04-11 US disclosed
US-20230042417-A1 METHOD OF PREPARING SILICONE-ACRYLATE HYBRID COMPOSITION AND HYBRID COMPOSITION FORMED THEREBY DOW GLOBAL TECHNOLOGIES LLC 2023-02-09 US disclosed
EP-4085086-A1 METHOD OF PREPARING SILICONE-ACRYLATE HYBRID COMPOSITION AND HYBRID COMPOSITION FORMED THEREBY Dow Silicones Corporation (US) 2022-11-09 EP disclosed
WO-2021138191-A1 METHOD OF PREPARING SILICONE-ACRYLATE HYBRID COMPOSITION AND HYBRID COMPOSITION FORMED THEREBY DOW SILICONES CORPORATION (US) 2021-07-08 WO disclosed
US-20210163743-A1 PHOTOCURABLE SILICONE COMPOSITION DOW SILICONES CORPORATION 2021-06-03 US disclosed
EP-0615962-A1 Process for preparing ceramic fibers from polysiloxanes DOW CORNING CORPORATION (US) 1994-09-21 EP disclosed
US-5302627-A For polysiloxanes DOW CORNING CORPORATION (US) 1994-04-12 US disclosed
US-5179619-A Multilayer coatings with photoinitiators PIRELLI CAVI S.P.A. (IT) 1993-01-12 US disclosed
EP-0492830-A2 Method of indicating a cure point for ultraviolet radiation curing compositions by color change DOW CORNING CORPORATION (US) 1992-07-01 EP disclosed
EP-0487121-A1 Optical fibre element comprising a polyacrylate coating layer reticulated by UV radiation and an H2-absorbing buffer PIRELLI CAVI S.p.A. (IT) 1992-05-27 EP disclosed
US-5063102-A Ultraviolet, polymethylsiloxane, mercaptan curing agent, photoinitiator; protecting electronic devices against environment by coating or encapsulating with cured composition DOW CORNING CORPORATION (US) 1991-11-05 US disclosed
EP-0430273-A2 Radiation curable organosiloxane gel compositions DOW CORNING CORPORATION (US) 1991-06-05 EP disclosed
US-4987159-A HIGH EFFICIENCY FRATELLI LAMBERTI S.P.A. (IT) 1991-01-22 US disclosed