SCHEMBL7028833

SCHEMBL7028833

CCC(O)c1ccccc1C=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.45
MEN1 O00255 1/20 0.44
THRB P10828 1/20 0.44
BLM P54132 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
TRIM24 O15164 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
HPGD P15428 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HTT P42858 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.36
ERN1 O75460 3/20 0.35
GAA P10253 1/20 0.35
TLR2 O60603 1/20 0.34
TLR1 Q15399 1/20 0.34
TLR6 Q9Y2C9 1/20 0.34
SRC P12931 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12760884 0.85 LMNA (0.41) LMNAMEN1THRBBLMKMT2A
SCHEMBL5560713 0.82 LMNA (0.47) LMNAALDH1A1TSHRPDE2ATP53
SCHEMBL8082979 0.82 PPARG (0.45) LMNAMEN1THRBBLMKMT2A
SCHEMBL7025538 0.81 LMNA (0.35) LMNAMEN1THRBBLMKMT2A
SCHEMBL11678133 0.81 LMNA (0.44) LMNAMEN1THRBBLMKMT2A
SCHEMBL10497320 0.80 LMNA (0.48) LMNAMEN1THRBBLMKMT2A
SCHEMBL5107136 0.79 LMNA (0.61) LMNABLMTSHRPDE2A
SCHEMBL5107130 0.79 LMNA (0.61) LMNABLMTSHRPDE2A
SCHEMBL30172716 0.79 LMNA (0.61) LMNABLMTSHRPDE2A
SCHEMBL5107133 0.79 LMNA (0.61) LMNABLMTSHRPDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933343-B1 Method for producing sized, coated ceramic fibers COI CERAMICS INC (US) 2003-06-25 EP claimed
US-6251520-B1 APPLYING NON-AQUEOUS SIZING TO CERAMIC FIBER; CURING DOW CORNING CORPORATION 2001-06-26 US claimed
EP-0933343-A1 Method for producing sized, coated ceramic fibers DOW CORNING CORPORATION (US) 1999-08-04 EP claimed
CN-108008600-B Radiation-sensitive composition 三菱瓦斯化学株式会社 2021-02-09 CN disclosed
EP-2505576-B1 CYCLIC COMPOUND, PROCESS FOR PRODUCTION THEREOF, RADIATION-SENSITIVE COMPOSITION, AND RESIST PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL CO (JP) 2019-04-24 EP disclosed
US-8969629-B2 Cyclic compound, production process thereof, radiation-sensitive composition and resist pattern formation method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-03-03 US disclosed
US-20120282546-A1 CYCLIC COMPOUND, PRODUCTION PROCESS THEREOF, RADIATION-SENSITIVE COMPOSITION AND RESIST PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-11-08 US disclosed
EP-2505576-A1 CYCLIC COMPOUND, PROCESS FOR PRODUCTION THEREOF, RADIATION-SENSITIVE COMPOSITION, AND RESIST PATTERN FORMATION METHOD Mitsubishi Gas Chemical Company, Inc. (JP) 2012-10-03 EP disclosed
EP-0933343-B1 Method for producing sized, coated ceramic fibers COI CERAMICS INC (US) 2003-06-25 EP disclosed
US-6251520-B1 APPLYING NON-AQUEOUS SIZING TO CERAMIC FIBER; CURING DOW CORNING CORPORATION 2001-06-26 US disclosed
EP-0933343-A1 Method for producing sized, coated ceramic fibers DOW CORNING CORPORATION (US) 1999-08-04 EP disclosed
EP-0487121-B1 Optical fibre element comprising a polyacrylate coating layer reticulated by UV radiation and an H2-absorbing buffer PIRELLI CAVI SPA (IT) 1996-08-28 EP disclosed
US-5179619-A Multilayer coatings with photoinitiators PIRELLI CAVI S.P.A. (IT) 1993-01-12 US disclosed
EP-0487121-A1 Optical fibre element comprising a polyacrylate coating layer reticulated by UV radiation and an H2-absorbing buffer PIRELLI CAVI S.p.A. (IT) 1992-05-27 EP disclosed
US-4987159-A HIGH EFFICIENCY FRATELLI LAMBERTI S.P.A. (IT) 1991-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120282546-A1 CYCLIC COMPOUND, PRODUCTION PROCESS THEREOF, RADIATION-SENSITIVE COMPOSITION AND RESIST PATTERN FORMATION METHOD CROCC, XRCC6, CHEK1 LMNA 1438/4885MEN1 1009/4885THRB 4202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.