Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 5/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611510 | 0.87 | GPR84 (0.47) | GPR84ATMMEN1KMT2AMAPT | |
| SCHEMBL27663377 | 0.84 | GPR84 (0.43) | GPR84ATMMEN1KMT2AMAPT | |
| SCHEMBL6091133 | 0.84 | NR4A2 (0.46) | GPR84ATMMEN1KMT2AMAPT | |
| SCHEMBL19059561 | 0.83 | GPR84 (0.47) | GPR84ATMMEN1KMT2AMAPT | |
| SCHEMBL8402932 | 0.81 | GPR84 (0.50) | GPR84ATMMEN1KMT2AMAPT | |
| SCHEMBL5851463 | 0.81 | GPR84 (0.47) | GPR84ATMMEN1KMT2AMAPT | |
| SCHEMBL30969153 | 0.80 | GPR84 (0.46) | GPR84ATMMEN1KMT2AMAPT | |
| SCHEMBL18923935 | 0.80 | GPR84 (0.46) | GPR84ATMMEN1KMT2AMAPT | |
| SCHEMBL25439220 | 0.79 | MEN1 (0.46) | GPR84ATMMEN1KMT2AMAPT | |
| SCHEMBL29611302 | 0.78 | HTR2A (0.47) | GPR84ATMMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328513-A2 | DIINDOLYLMETHANE AND C-SUBSTITUTED DIINDOLYLMETHANE COMPOSITIONS AND METHODS FOR THE TREATMENT OF MULTIPLE CANCERS | The Texas A & M University System (US) | 2003-07-23 | — | — | EP | claimed |
| WO-2002028832-A2 | DIINDOLYLMETHANE AND C-SUBSTITUTED DIINDOLYLMETHANE COMPOSITIONS AND METHODS FOR THE TREATMENT OF MULTIPLE CANCERS | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2002-04-11 | — | — | WO | claimed |