Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 8/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11722694 | 0.82 | ADORA1 (0.44) | ADORA1ADORA2AADORA2BKMT2AADORA3 | |
| SCHEMBL11717758 | 0.80 | ADORA1 (0.43) | ADORA1ADORA2AADORA2BKMT2ACSNK1A1 | |
| Metamitron SCHEMBL66369 | 0.80 | KDM4E (0.49) | ADORA1ADORA2BKMT2AADORA3NPC1 | |
| Metamitron SCHEMBL8536394 | 0.80 | KDM4E (0.49) | ADORA1ADORA2BKMT2AADORA3NPC1 | |
| SCHEMBL11064095 | 0.80 | ADORA1 (0.54) | ADORA1ADORA2AADORA2BCSNK1A1CLK4 | |
| SCHEMBL11385843 | 0.80 | ADORA1 (0.43) | ADORA1ADORA2AADORA2BKMT2ACSNK1A1 | |
| SCHEMBL11602304 | 0.76 | ALDH1A1 (0.49) | ADORA1ADORA2BKMT2AADORA3KDM4E | |
| SCHEMBL10508760 | 0.76 | ALDH1A1 (0.61) | ADORA1ADORA2BKMT2ACSNK1A1CLK4 | |
| SCHEMBL11609509 | 0.76 | ALDH1A1 (0.48) | ADORA1ADORA2AADORA2BKMT2ANPC1 | |
| SCHEMBL11715949 | 0.76 | ADORA1 (0.43) | ADORA1ADORA2AADORA2BKMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889884-B1 | 1,2,4-TRIAZINE DERIVATIVES FOR THE INHIBITION OF PROTEIN GLYCOSYLATION | ALTEON INC (US) | 2003-01-29 | — | — | EP | disclosed |
| US-4036632-A | CONTROLLING WEEDS USING 3-METHYLTHIO-4-AMINO-6-BUTYL-1,2,4 TRIAZINE-5-ONE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
| US-3966715-A | 1,2,4-TRIAZINE-5-ONES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
| US-3961936-A | SUBSTITUTED 1,2,4-TRIAZINE-5-ONES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |