Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.44 |
| ▸ | CDK8 | P49336 | 2/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029182 | 0.80 | ADORA1 (0.44) | ADORA1ADORA2BALDH1A1KDM4EHPGD | |
| SCHEMBL9843278 | 0.76 | ADORA1 (0.51) | ADORA1ADORA2BALDH1A1KDM4EGAA | |
| SCHEMBL10841723 | 0.76 | KDM4E (0.54) | ADORA1ADORA2BALDH1A1KDM4EGAA | |
| SCHEMBL11813567 | 0.76 | ADORA2B (0.51) | ADORA1ADORA2BALDH1A1KDM4EGAA | |
| SCHEMBL11808587 | 0.76 | ADORA1 (0.51) | ADORA1ADORA2BALDH1A1KDM4EGAA | |
| SCHEMBL10843009 | 0.75 | KDM4E (0.53) | ADORA1ADORA2BALDH1A1KDM4EGAA | |
| SCHEMBL13872765 | 0.73 | KMT2A (0.54) | ADORA1ADORA2BALDH1A1CYP1A2CYP3A4 | |
| Metamitron SCHEMBL8536394 | 0.71 | KDM4E (0.49) | ADORA1ADORA2BALDH1A1KDM4EGAA | |
| Metamitron SCHEMBL66369 | 0.71 | KDM4E (0.49) | ADORA1ADORA2BALDH1A1KDM4EGAA | |
| SCHEMBL11609509 | 0.68 | ALDH1A1 (0.48) | ADORA1ADORA2BALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447258-A | 3-Dimethylamino-4-methyl-1,2,4-triazin-5(4H)-ones and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1984-05-08 | — | — | US | disclosed |
| EP-0015452-B1 | 6-SUBSTITUTED-3-DIMETHYLAMINO-4-METHYL-1,2,4-TRIAZIN-5-(4H)-ONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1982-01-20 | — | — | EP | disclosed |
| EP-0015452-A1 | 6-Substituted-3-dimethylamino-4-methyl-1,2,4-triazin-5-(4H)-ones, processes for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-17 | — | — | EP | disclosed |