SCHEMBL7029219

SCHEMBL7029219

CC(=O)N1CCC[C@H]1C(=O)N(C)C

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 6/20 0.41
CHRM4 P08173 6/20 0.41
CHRM5 P08912 6/20 0.41
CHRM1 P11229 6/20 0.41
CHRM3 P20309 6/20 0.41
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
DPP4 P27487 2/20 0.37
PREP P48147 1/20 0.37
FAP Q12884 1/20 0.37
CCR1 P32246 1/20 0.36
P2RX7 Q99572 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14676527 0.85 ACE (0.39) DPP4
SCHEMBL14676528 0.85 ACE (0.39) DPP4
SCHEMBL16529795 0.85 ACE (0.39) DPP4
SCHEMBL3931689 0.83 CASP3 (0.38) DPP4PREPCCR1
SCHEMBL19065845 0.82 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL17309478 0.82 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL14311867 0.81 DPP4 (0.35) DPP4PREPCCR1
SCHEMBL12424180 0.80 CCR1 (0.46) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL25919872 0.80 ACE (0.46) DPP4PREPFAPCCR1
SCHEMBL8844173 0.80 CCR1 (0.46) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0804231-B1 SYNTHETIC MULTIPLE TANDEM REPEAT MUCIN AND MUCIN-LIKE PEPTIDES, AND USES THEREOF FINN OLIVERA J (US) 2003-02-05 EP disclosed
EP-0804231-A4 SYNTHETIC MULTIPLE TANDEM REPEAT MUCIN AND MUCIN-LIKE PEPTIDES, AND USES THEREOF FINN OLIVERA J (US) 1999-08-18 EP disclosed
US-5827666-A FOR DETECTING ANTIBODIES TO PANCREATIC, BREAST, COLON CANCER UNIVERSITY OF PITTSBURGH (US) 1998-10-27 US disclosed
US-5744144-A CANCER VACCINE UNIVERSITY OF PITTSBURGH UNIVERSITY PATENT COMMITTEE POLICY AND PROCEDURES (US) 1998-04-28 US disclosed
EP-0804231-A1 SYNTHETIC MULTIPLE TANDEM REPEAT MUCIN AND MUCIN-LIKE PEPTIDES, AND USES THEREOF Finn, Olivera J. (US) 1997-11-05 EP disclosed
WO-1995003825-A1 SYNTHETIC MULTIPLE TANDEM REPEAT MUCIN AND MUCIN-LIKE PEPTIDES, AND USES THEREOF FINN OLIVERA J (US) 1995-02-09 WO disclosed