Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12424180 | 1.00 | CCR1 (0.46) | CCR1BCHECHRM2CHRM4CHRM5 | |
| SCHEMBL2757932 | 0.81 | LMNA (0.39) | CCR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7029219 | 0.80 | CHRM2 (0.41) | CCR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL12733430 | 0.79 | BCHE (0.47) | CCR1BCHEDPP4KDM4E | |
| SCHEMBL12655765 | 0.77 | P2RX7 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL21341259 | 0.77 | P2RX7 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12359031 | 0.75 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL1943156 | 0.75 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL13629804 | 0.75 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL27918507 | 0.75 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5609876-A | Peptide vaccines and associated methods for protection against feline leukemia virus | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1997-03-11 | — | — | US | disclosed |