SCHEMBL7029478

SCHEMBL7029478

CCP(C)(=O)OCC(C)C

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13541606 0.82 ALDH1A1 (0.35) ALDH1A1CYP3A4GAANPSR1KDM4E
SCHEMBL8970852 0.82 ALDH1A1 (0.35) ALDH1A1CYP3A4GAANPSR1KDM4E
SCHEMBL8150189 0.81 TRPM8 (0.34) ALDH1A1CYP3A4GAANPSR1
SCHEMBL11596411 0.78 CYP3A4 (0.35) TSHRALDH1A1CYP3A4GAANPSR1
SCHEMBL3987245 0.77 TSHR (0.55) TSHRALDH1A1CYP3A4GAANPSR1
SCHEMBL8971191 0.76
SCHEMBL5407738 0.76 NPSR1 (0.39) TSHRALDH1A1CYP3A4GAANPSR1
SCHEMBL10613882 0.75 ALDH1A1 (0.31) ALDH1A1CYP3A4GAANPSR1
SCHEMBL11593856 0.75 PPARD (0.40) ALDH1A1CYP3A4GAANPSR1MEN1
SCHEMBL11593847 0.75 CYP3A4 (0.37) ALDH1A1CYP3A4GAANPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1055676-B1 Process for the preparation of dialkylphosphinic acids and their salts CLARIANT GMBH (DE) 2003-08-06 EP disclosed
EP-0923586-B1 Phosphinic acid aluminium salts TICONA GMBH (DE) 2003-03-05 EP disclosed
EP-0944637-B1 PROCESS FOR PREPARING ALUMINIUM SALTS OF DIALKYLPHOSPHINIC ACIDS AND DIPHOSPHINIC ACIDS TICONA GMBH (DE) 2002-04-10 EP disclosed
US-6194605-B1 REACTING DIALKYLPHOSPHINIC ACID ESTER OR DIPHOSPHINIC ACID ESTER IN PRESENCE OF SOLVENT AND REACTION SATURATED ALIPHATIC MONOCARBOXYLIC ACID WITH ALUMINUM HYDROXIDE IN A CLOSED PRESSURE-RESISTANT REACTION VESSEL TICONA GMBH (DE) 2001-02-27 US disclosed
EP-1055676-A1 Process for the preparation of dialkylphosphinic acids and their salts Clariant GmbH (DE) 2000-11-29 EP disclosed
EP-0944637-A2 PROCESS FOR PREPARING ALUMINIUM SALTS OF DIALKYLPHOSPHINIC ACIDS AND DIPHOSPHINIC ACIDS Ticona GmbH (DE) 1999-09-29 EP disclosed
EP-0923586-A1 PHOSPHINIC ACID ALUMINIUM SALTS Ticona GmbH (DE) 1999-06-23 EP disclosed
US-5900469-A Storage-stable, phosphorus-modified epoxy resins AVENTIS RESEARCH & TECHNOLOGIES GMBH (DE) 1999-05-04 US disclosed
WO-1998025937-A2 PROCESS FOR PREPARING ALUMINIUM SALTS OF DIALKYLPHOSPHINIC ACIDS AND DIPHOSPHINIC ACIDS TICONA GMBH (DE) 1998-06-18 WO disclosed
WO-1998003515-A1 PHOSPHINIC ACID ALUMINIUM SALTS TICONA GMBH (DE) 1998-01-29 WO disclosed
EP-0794205-A1 Storage stable, phosphorus-modified epoxy resins HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-10 EP disclosed
EP-0071957-B1 PROCESS FOR THE POLYMERISATION OF 1-OLEFINS AND PROCESS FOR PREPARING THE CATALYST USED THEREIN HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-05 EP disclosed
EP-0071957-A2 Process for the polymerisation of 1-olefins and process for preparing the catalyst used therein HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-16 EP disclosed
US-4329256-A Process for the manufacture of a mixed catalyst HOECHST AKTIENGESELLSCHAFT (DE) 1982-05-11 US disclosed
US-4138433-A Process for preparing 1,2-oxa-phospholanes HOECHST AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed