SCHEMBL7029671

SCHEMBL7029671

ClCCCSCc1cccs1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
ALDH1A1 P00352 3/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
HPGD P15428 1/20 0.42
MAPT P10636 2/20 0.42
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
HTT P42858 1/20 0.41
POLB P06746 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
MAOB P27338 1/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
CYP2C19 P33261 1/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
ACHE P22303 6/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9215812 0.82 TAAR1 (0.53) TAAR1SMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL9218766 0.82 TAAR1 (0.53) TAAR1SMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL5104616 0.81 ALDH1A1 (0.44) TAAR1SMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL9220272 0.81 TAAR1 (0.57) TAAR1SMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL9212292 0.80 TAAR1 (0.55) TAAR1SMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL5144954 0.80 ALDH1A1 (0.51) TAAR1SMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL2585841 0.79 ALDH1A1 (0.45) TAAR1SMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL9218659 0.77 TAAR1 (0.55) TAAR1SMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL9217829 0.77 ALDH1A1 (0.47) TAAR1SMN1; SMN2ALDH1A1NPC1RAB9A
Hydrochloric Acid SCHEMBL10746622 0.76 TAAR1 (0.53) TAAR1SMN1; SMN2ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0920441-B1 7ALPHA-(EPSILON-AMINOALKYL)-ESTRATRIENES, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 7ALPHA-(EPSILON-AMINOALKYL)-ESTRATRIENES AND THEIR USE FOR PREPARING MEDICAMENT SCHERING AG (DE) 2003-01-29 EP disclosed
US-6271403-B1 PURE ANTIESTROGENS, OR ESTROGENIC ANTIESTROGENS WITH ESTROGENIC PARTIAL ACTION. SCHERING AKTIENGESELLSCHAFT (DE) 2001-08-07 US disclosed
US-5986115-A STEROIDS WITH FLUORO GROUPS AND ETHER OR ESTER GROUPS SCHERING AG (DE) 1999-11-16 US disclosed
EP-0920441-A1 7ALPHA-(EPSILON-AMINOALKYL)-ESTRATRIENES, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 7ALPHA-(EPSILON-AMINOALKYL)-ESTRATRIENES AND THEIR USE FOR PREPARING MEDICAMENT SCHERING AKTIENGESELLSCHAFT (DE) 1999-06-09 EP disclosed
US-5866560-A ESTROGEN INHIBITORS; TUMOR THERAPY; HORMONE REPLACEMENT THERAPY SCHERING AG (DE) 1999-02-02 US disclosed
WO-1998007740-A1 7α-(κ-AMINOALKYL)ESTRATRIENES, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 7α-(κ-AMINOALKYL)ESTRATRIENES AND THEIR USE FOR PREPARING MEDICAMENTS SCHERING AKTIENGESELLSCHAFT (DE) 1998-02-26 WO disclosed