Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144954 | 0.84 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9218659 | 0.82 | TAAR1 (0.55) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9217829 | 0.82 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL10746622 | 0.80 | TAAR1 (0.53) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL5104616 | 0.79 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL7029671 | 0.79 | TAAR1 (0.42) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9220272 | 0.79 | TAAR1 (0.57) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9212292 | 0.77 | TAAR1 (0.55) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL8305122 | 0.76 | CYP2C19 (0.56) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9215812 | 0.76 | TAAR1 (0.53) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130231334-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT APHIDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-05 | — | — | US | disclosed |
| EP-2563118-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT APHIDS | Syngenta Participations AG (CH) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011134819-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT APHIDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130231334-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT APHIDS | DDT, AGO2, INF2 | ALDH1A1 4499/4885SMN1; SMN2 948/4885NPC1 2554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.