SCHEMBL70297

SCHEMBL70297

O=[N+]([O-])c1cccnc1SSc1ncccc1[N+](=O)[O-]

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
ALDH1A1 P00352 3/20 0.56
GAA P10253 2/20 0.56
PKM P14618 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MAPT P10636 4/20 0.55
PDE10A Q9Y233 1/20 0.55
POLB P06746 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
MAPK1 P28482 1/20 0.50
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 2/20 0.49
NCOA1 Q15788 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.49
CYP2C19 P33261 1/20 0.49
RAB9A P51151 2/20 0.47
LMNA P02545 2/20 0.45
PAX8 Q06710 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29627490 1.00 MEN1 (0.61) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL1763611 0.92 MEN1 (0.58) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL29938229 0.92 MEN1 (0.58) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL13596619 0.89 SMN1; SMN2 (0.58) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL1763613 0.89 MEN1 (0.55) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL23870561 0.89 MEN1 (0.55) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL31676628 0.89 SMN1; SMN2 (0.58) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL6849222 0.88 MEN1 (0.71) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL4988971 0.85 SMN1; SMN2 (0.61) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL70296 0.85 MEN1 (0.58) MEN1KMT2AALDH1A1GAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4634 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110621673-A Double-stranded linked cytotoxic drug conjugates 杭州多禧生物科技有限公司 2019-12-27 CN claimed
EP-2648510-B1 METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS IMMUNOGEN INC (US) 2016-08-31 EP claimed
US-9242936-B2 Methods for the preparation of charged crosslinkers IMMUNOGEN, INC. (US) 2016-01-26 US claimed
US-20150166482-A1 METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS IMMUNOGEN, INC. 2015-06-18 US claimed
US-8754039-B2 Targeted antimicrobial moieties C3 JIAN, INC. (US) 2014-06-17 US claimed
US-8598362-B2 Methods for the preparation of charged crosslinkers IMMUNOGEN, INC. (US) 2013-12-03 US claimed
EP-2648510-A1 METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS ImmunoGen, Inc. (US) 2013-10-16 EP claimed
US-20120165537-A1 METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS IMMUNOGEN, INC. (US) 2012-06-28 US claimed
WO-2012078868-A1 METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS IMMUNOGEN, INC. (US) 2012-06-14 WO claimed
US-RE35524-E Epipodophyllotoxin glucoside 4'-phosphate derivatives BRISTOL-MYERS SQUIBB COMPANY (US) 1997-06-03 US claimed
US-4904768-A Epipodophyllotoxin glucoside 4'-phosphate derivatives BRISTOL-MYERS COMPANY (US) 1990-02-27 US claimed
EP-3620473-B1 NOVEL HETERODIMERIC PROTEINS XENCOR INC (US) 2026-05-27 EP disclosed
EP-4748862-A2 HETERODIMERIC PROTEINS Xencor, Inc. (US) 2026-05-27 EP disclosed
EP-3865514-B9 BISPECIFIC ANTIBODY BINDING DLL3 AND CD3 AMGEN RES MUNICH GMBH (DE) 2026-05-20 EP disclosed
US-12630650-B2 Engineered IgA antibodies and methods of use TIGATX, INC. (US) 2026-05-19 US disclosed
WO-1989012678-A1 PURIFIED UBIQUITIN HYDROLASE, DNA SEQUENCES ENCODING SAME, AND ITS USE IN RECOVERING POLYPEPTIDES GENENTECH, INC. (US) 1989-12-28 WO disclosed
EP-0339695-A2 A process for preparing an antigenic or immunogenic conjugate as well as the use of such conjugates STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 1989-11-02 EP disclosed
WO-1988009376-A1 METHOD AND COMPOSITIONS FOR MAKING ACSF AND ACSF ANTAGONISTS GENENTECH, INC. (US) 1988-12-01 WO disclosed
US-4406885-A Preparation of native oncornavirus envelope subunits and vaccines therefrom RESEARCH CORPORATION (US) 1983-09-27 US disclosed
US-4009168-A STABILIZERS FOR POLYOLEFINS UBE INDUSTRIES, LTD. (JA) 1977-02-22 US disclosed