SCHEMBL29627490

SCHEMBL29627490

O=[N+]([O-])c1cccnc1SSc1ncccc1[N+](=O)[O-]

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
ALDH1A1 P00352 3/20 0.56
GAA P10253 2/20 0.56
PKM P14618 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MAPT P10636 4/20 0.55
PDE10A Q9Y233 1/20 0.55
POLB P06746 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
MAPK1 P28482 1/20 0.50
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 2/20 0.49
NCOA1 Q15788 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.49
CYP2C19 P33261 1/20 0.49
RAB9A P51151 2/20 0.47
LMNA P02545 2/20 0.45
PAX8 Q06710 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70297 1.00 MEN1 (0.61) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL1763611 0.92 MEN1 (0.58) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL29938229 0.92 MEN1 (0.58) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL13596619 0.89 SMN1; SMN2 (0.58) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL1763613 0.89 MEN1 (0.55) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL23870561 0.89 MEN1 (0.55) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL31676628 0.89 SMN1; SMN2 (0.58) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL6849222 0.88 MEN1 (0.71) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL4988971 0.85 SMN1; SMN2 (0.61) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL70296 0.85 MEN1 (0.58) MEN1KMT2AALDH1A1GAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719450-A2 MODIFIED CAVEOLIN-1 PEPTIDE FORMULATIONS AND METHODS OF MANUFACTURING AND USE THEREOF Rein Therapeutics, Inc. (US) 2026-04-08 EP disclosed
EP-4673477-A1 CONDITIONALLY ACTIVE ANTI-EPCAM ANTIBODIES, ANTIBODY FRAGMENTS AND CONSTRUCTS INCORPORATING SAME BioAtla, Inc. (US) 2026-01-07 EP disclosed
EP-4554605-A2 MODIFIED CAVEOLIN-1 PEPTIDE FORMULATIONS AND METHODS OF MANUFACTURING AND USE THEREOF Rein Therapeutics, Inc. (US) 2025-05-21 EP disclosed
EP-4522651-A1 MULTICHAIN MULTITARGETING BISPECIFIC ANTIGEN-BINDING MOLECULES OF INCREASED SELECTIVITY Amgen Research (Munich) GmbH (DE) 2025-03-19 EP disclosed
WO-2025029690-A1 ENGINEERED IGA ANTIBODIES AND METHODS OF USE TIGATX, INC. (US) 2025-02-06 WO disclosed
WO-2024249565-A2 MODIFIED CAVEOLIN-1 PEPTIDE FORMULATIONS AND METHODS OF MANUFACTURING AND USE THEREOF LUNG THERAPEUTICS, LLC (US) 2024-12-05 WO disclosed
US-12090211-B2 Methods for preparing antibody drug conjugates GENENTECH, INC. (US) 2024-09-17 US disclosed
WO-2024182645-A1 CONDITIONALLY ACTIVE ANTI-EPCAM ANTIBODIES, ANTIBODY FRAGMENTS AND CONSTRUCTS INCORPORATING SAME BIOATLA, INC. (US) 2024-09-06 WO disclosed
EP-4347622-A1 RECONSTITUTION AND USES OF FLAVIVIRUS EPITOPES Ramot at Tel-Aviv University Ltd. (IL) 2024-04-10 EP disclosed
EP-4337676-A1 ANTIGEN-BINDING AND ANTIGEN DEGRADATION CONSTRUCTS Entrada Therapeutics, Inc. (US) 2024-03-20 EP disclosed
WO-2023154916-A2 COMPOSITIONS AND METHODS FOR TREATING INFECTIOUS DISEASES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-08-17 WO disclosed
US-20230233700-A1 METHODS FOR PREPARING ANTIBODY DRUG CONJUGATES GENENTECH, INC. (US) 2023-07-27 US disclosed
EP-4135738-A2 METHOD OF TREATING CORONAVIRUS INFECTIONS Cohbar Inc. (US) 2023-02-22 EP disclosed
US-11547762-B2 Methods for preparing antibody drug conjugates GENENTECH, INC. (US) 2023-01-10 US disclosed
WO-2022254433-A1 RECONSTITUTION AND USES OF FLAVIVIRUS EPITOPES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-12-08 WO disclosed
WO-2022240757-A1 ANTIGEN-BINDING AND ANTIGEN DEGRADATION CONSTRUCTS ENTRADA THERAPEUTICS, INC. (US) 2022-11-17 WO disclosed
WO-2022217037-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF CHRONIC LUNG DISEASES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-10-13 WO disclosed
WO-2022133361-A2 POLYPEPTIDES, VACCINE COMPOSITIONS, AND USE THEREOF FOR INDUCING IMMUNE RESPONSE TO SARS-COV-2 IN PRIMATES ZHANG KANG (US) 2022-06-23 WO disclosed
WO-2022096716-A2 MULTITARGETING BISPECIFIC ANTIGEN-BINDING MOLECULES OF INCREASED SELECTIVITY AMGEN INC. (US) 2022-05-12 WO disclosed
WO-2022087224-A1 METHOD OF TREATING FIBROSIS WITH A COMBINATION THERAPY COHBAR, INC. (US) 2022-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230233700-A1 METHODS FOR PREPARING ANTIBODY DRUG CONJUGATES FCGRT, MSN, FCGR3B MEN1 982/4885KMT2A 448/4885ALDH1A1 272/4885
US-11547762-B2 Methods for preparing antibody drug conjugates FCGRT, MSN, FCGR3B MEN1 982/4885KMT2A 448/4885ALDH1A1 272/4885
US-12090211-B2 Methods for preparing antibody drug conjugates FCGRT, MSN, FCGR3B MEN1 982/4885KMT2A 448/4885ALDH1A1 272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.