Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | LCT | P09848 | 2/20 | 0.32 |
| ▸ | UGCG | Q16739 | 2/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 3/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7032403 | 0.93 | GBA1 (0.33) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7024993 | 0.90 | ESR2 (0.33) | ESR2GBA1LCTUGCGGBA2 | |
| SCHEMBL7030104 | 0.88 | CYP2C9 (0.39) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7030241 | 0.88 | GBA1 (0.33) | CYP2C9ESR2GBA1LCTUGCG | |
| SCHEMBL7027474 | 0.88 | CYP2C9 (0.42) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7033562 | 0.85 | GBA1 (0.34) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL7027057 | 0.85 | FFAR4 (0.33) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8389623 | 0.85 | FFAR4 (0.32) | CYP2C9GBA1LCTUGCGGBA2 | |
| SCHEMBL7031162 | 0.84 | CYP2C9 (0.43) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8725021 | 0.83 | GBA1 (0.31) | GBA1LCTUGCGGBA2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |