Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | LCT | P09848 | 2/20 | 0.33 |
| ▸ | UGCG | Q16739 | 2/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029773 | 0.93 | CYP2C9 (0.39) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL7032295 | 0.89 | KDM5A (0.31) | CYP2C9MAPTGAA | |
| SCHEMBL8389685 | 0.89 | KDM5A (0.31) | CYP2C9MAPTGAA | |
| SCHEMBL7026846 | 0.89 | CYP2C9 (0.33) | CYP2C9MAPTGAAALDH1A1LMNA | |
| SCHEMBL7029011 | 0.89 | CYP2C9 (0.35) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL7024993 | 0.88 | ESR2 (0.33) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL8389581 | 0.86 | KDM5A (0.32) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL7032811 | 0.86 | KDM5A (0.32) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8385805 | 0.85 | GBA1 (0.31) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL7030241 | 0.85 | GBA1 (0.33) | GBA1LCTUGCGGBA2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |