Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10670385 | 0.85 | CA1 (0.55) | MAPK1POLBTSHRPAX8LMNA | |
| SCHEMBL9349435 | 0.83 | MAPK1 (0.40) | MAPK1POLBTSHRPAX8HTT | |
| SCHEMBL9350273 | 0.83 | POLB (0.40) | MAPK1POLBTSHRPAX8LMNA | |
| SCHEMBL5809527 | 0.83 | MAPK1 (0.59) | MAPK1POLBTSHRPAX8LMNA | |
| SCHEMBL7031880 | 0.83 | MAPK1 (0.59) | MAPK1POLBTSHRPAX8LMNA | |
| SCHEMBL20892712 | 0.82 | MAPK1 (0.68) | MAPK1POLBTSHRLMNAHTT | |
| SCHEMBL28217544 | 0.82 | ALDH1A1 (0.45) | MAPK1POLBTSHRLMNAHTT | |
| SCHEMBL11456408 | 0.82 | ALDH1A1 (0.52) | MAPK1POLBLMNAHTTSMN1; SMN2 | |
| SCHEMBL20314685 | 0.81 | MAPK1 (0.58) | MAPK1POLBTSHRPAX8LMNA | |
| SCHEMBL10409516 | 0.81 | CA9 (0.42) | MAPK1POLBTSHRALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841323-B1 | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL CO (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-5902905-A | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0841323-A2 | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-05-13 | — | — | EP | disclosed |