Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 7/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11456408 | 0.89 | ALDH1A1 (0.52) | ALDH1A1TDP1LMNAL3MBTL1NPSR1 | |
| SCHEMBL10911117 | 0.86 | TXNRD1 (0.48) | ALDH1A1TDP1LMNASIRT6TXNRD1 | |
| SCHEMBL29812082 | 0.86 | TXNRD1 (0.48) | ALDH1A1TDP1LMNASIRT6TXNRD1 | |
| SCHEMBL31363261 | 0.82 | TXNRD1 (0.50) | ALDH1A1TDP1LMNASIRT6TXNRD1 | |
| SCHEMBL7029977 | 0.82 | MAPK1 (0.59) | ALDH1A1LMNANPSR1MAPK1POLB | |
| SCHEMBL15824942 | 0.80 | ALDH1A1 (0.51) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL30184523 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL6522436 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL28826257 | 0.78 | POLB (0.47) | ALDH1A1TDP1LMNASIRT6TXNRD1 | |
| SCHEMBL15823469 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TDP1LMNASIRT6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947728-B | Sulfonyl-containing dihydropteridinone derivatives and their use | 沈阳药科大学 | 2024-01-09 | — | — | CN | disclosed |
| CN-108047204-A | 2,4- diarylamino pyrimidine derivatives and its preparation method and application | 沈阳药科大学 | 2018-05-18 | — | — | CN | disclosed |