Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | PARG | Q86W56 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29902418 | 0.82 | PKM (0.71) | ALDH1A1PKMGAAKMT2AMEN1 | |
| SCHEMBL29902387 | 0.81 | ALDH1A1 (0.59) | ALDH1A1PKMGAAKMT2AMEN1 | |
| SCHEMBL20202316 | 0.80 | ALDH1A1 (0.72) | ALDH1A1PKMGAAKMT2AMEN1 | |
| SCHEMBL11511836 | 0.80 | ALDH1A1 (0.83) | ALDH1A1KMT2ATSHRSMN1; SMN2MAPK1 | |
| SCHEMBL11202734 | 0.79 | PKM (0.61) | ALDH1A1PKMGAAKMT2AMEN1 | |
| SCHEMBL11204500 | 0.79 | PKM (0.61) | ALDH1A1PKMGAAKMT2AMEN1 | |
| SCHEMBL13159565 | 0.79 | PKM (0.93) | ALDH1A1PKMGAAKMT2AMEN1 | |
| SCHEMBL13183051 | 0.79 | PARG (0.59) | ALDH1A1PKMGAAKMT2AMEN1 | |
| SCHEMBL13159473 | 0.78 | ALDH1A1 (0.94) | ALDH1A1PKMGAAKMT2AMEN1 | |
| SCHEMBL11321975 | 0.77 | PKM (0.59) | ALDH1A1PKMGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833626-B1 | MONO- AND DISULFO-SUBSTITUTED ANTHRAQUINONES AND THEIR USE FOR THE TREATMENT OF BONE MATRIX DISORDERS | H GEN B V (NL) | 2003-03-05 | — | — | EP | claimed |
| US-5856358-A | PREVENT BONE EROSION | BOONVILLE LIMITED (VG) | 1999-01-05 | — | — | US | claimed |
| EP-0833626-B1 | MONO- AND DISULFO-SUBSTITUTED ANTHRAQUINONES AND THEIR USE FOR THE TREATMENT OF BONE MATRIX DISORDERS | H GEN B V (NL) | 2003-03-05 | — | — | EP | disclosed |
| US-5856358-A | PREVENT BONE EROSION | BOONVILLE LIMITED (VG) | 1999-01-05 | — | — | US | disclosed |
| EP-0833626-A1 | MONO- AND DISULFO-SUBSTITUTED ANTHRAQUINONES AND THEIR USE FOR THE TREATMENT OF BONE MATRIX DISORDERS | Boonville Limited (VG) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000675-A1 | MONO- AND DISULFO-SUBSTITUTED ANTHRAQUINONES AND THEIR USE FOR THE TREATMENT OF BONE MATRIX DISORDERS | BOONVILLE LIMITED (VG) | 1997-01-09 | — | — | WO | disclosed |