Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683962 | 0.86 | ADORA2B (0.62) | ADORA2BADORA2ALMNATSHRHTT | |
| SCHEMBL7037369 | 0.86 | ADORA2B (0.88) | ADORA2BADORA2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11388923 | 0.85 | ADORA2B (0.61) | ADORA2BADORA2ALMNATSHRHTT | |
| Diethylamine SCHEMBL11388706 | 0.85 | ADORA2B (0.64) | ADORA2BADORA2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL17626266 | 0.84 | ADORA2B (0.67) | ADORA2BADORA2ALMNATSHRSMN1; SMN2 | |
| Diethylamine SCHEMBL11388925 | 0.84 | ADORA2B (0.62) | ADORA2BADORA2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL8318291 | 0.83 | ADORA2B (0.58) | ADORA2BADORA2ALMNATSHRHTT | |
| SCHEMBL4146728 | 0.83 | ADORA2B (1.00) | ADORA2BADORA2AHTTSMN1; SMN2HPGD | |
| SCHEMBL10395302 | 0.81 | ADORA2B (0.63) | ADORA2BADORA2AHPGDALDH1A1 | |
| SCHEMBL515794 | 0.78 | ADORA2B (0.74) | ADORA2BADORA2AHTTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956855-B1 | Immunosuppressive effects of 8 substituted xanthine derivatives | LEUVEN K U RES & DEV (BE) | 2003-03-12 | — | — | EP | claimed |