Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683962 | 0.94 | ADORA2B (0.62) | ADORA2BADORA2AMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL11388923 | 0.93 | ADORA2B (0.61) | ADORA2BADORA2AMEN1KMT2ATSHR | |
| SCHEMBL683888 | 0.85 | SMN1; SMN2 (0.51) | ADORA2BADORA2AMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL11381649 | 0.84 | SMN1; SMN2 (0.50) | ADORA2BADORA2AMEN1KMT2ATSHR | |
| SCHEMBL7030152 | 0.83 | ADORA2B (0.70) | ADORA2BADORA2ATSHRLMNANPSR1 | |
| SCHEMBL684271 | 0.83 | TSHR (0.54) | ADORA2BADORA2AMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL11384998 | 0.82 | TSHR (0.53) | ADORA2BADORA2AMEN1KMT2ATSHR | |
| SCHEMBL683542 | 0.81 | NCOA3 (0.54) | ADORA2BADORA2AMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL11381068 | 0.81 | NCOA3 (0.53) | ADORA2BADORA2AMEN1KMT2ATSHR | |
| SCHEMBL682765 | 0.81 | MAOB (0.49) | ADORA2BADORA2ATP53MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067006-A1 | COMBINATION OF A PDE IV INHIBITOR AND A TNF-ALPHA ANTAGONIST | PHARMACIA CORPORATION (US) | 2004-08-12 | — | — | WO | disclosed |