SCHEMBL7030192

SCHEMBL7030192

COC(=O)C1SCC(Cl)C1=O

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
CYP1A2 P05177 2/20 0.34
HIF1A Q16665 1/20 0.34
BRD4 O60885 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7025197 0.81 KDM4E (0.38) KMT2AALDH1A1
SCHEMBL7026737 0.79 KMT2A (0.37) KMT2ACYP1A2HIF1ABRD4ALDH1A1
SCHEMBL7024458 0.78 PPM1B (0.35) ALDH1A1
SCHEMBL7029610 0.77 KMT2A (0.30) KMT2A
SCHEMBL7026744 0.75 KMT2A (0.35) KMT2ACYP1A2HIF1ABRD4ALDH1A1
SCHEMBL7024529 0.74 KMT2A (0.33) KMT2ACYP1A2HIF1ABRD4
SCHEMBL7472185 0.71 CYP1A2 (0.33) CYP1A2HIF1A
SCHEMBL11799388 0.69 CYP1A2 (0.37) KMT2ACYP1A2HIF1ABRD4ALDH1A1
SCHEMBL14887016 0.68 KMT2A (0.41) KMT2ABRD4ALDH1A1
SCHEMBL3058001 0.65 KMT2A (0.35) KMT2ACYP1A2HIF1ABRD4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030162979-A1 Substituted sulphonylamino(thio)carbonyl compounds MULLER KLAUS-HELMUT (DE) 2003-08-28 US disclosed
US-6441195-B1 2-ALKOXYCARBONYL-3-SULPHONAMIDE, SULPHONYL ISOCYANATE OR SULPHONYL ISOTHIOCYANATE-THIOPHENES; PRE- OR POSTEMERGENCE HERBICIDES; EFFICIENCY BAYER AKTIENGESELLSCHAFT (DE) 2002-08-27 US disclosed
US-6180567-B1 REACTING 2-ALKOXYCARBONYL-BENZENESULFONAMIDE DERIVATIVE WITH 1,2,4-(1H)TRIAZOLE-5-(THI)ONE DERIVATIVE BAYER AKTIENGESELLSCHAFT (DE) 2001-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162979-A1 Substituted sulphonylamino(thio)carbonyl compounds CBR3, CTH, CBR1 KMT2A 2161/4885CYP1A2 227/4885HIF1A 1030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.