Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030761 | 0.85 | KDM4E (0.38) | KMT2AGAAALDH1A1 | |
| SCHEMBL7032302 | 0.82 | PPM1B (0.35) | ALDH1A1 | |
| SCHEMBL7029250 | 0.80 | ALDH1A1 (0.31) | GAAALDH1A1 | |
| SCHEMBL7028041 | 0.79 | TSHR (0.33) | KMT2A | |
| SCHEMBL7026737 | 0.77 | KMT2A (0.37) | KMT2ABRD4CYP1A2HIF1AALDH1A1 | |
| SCHEMBL7030192 | 0.75 | KMT2A (0.36) | KMT2ABRD4CYP1A2HIF1AALDH1A1 | |
| SCHEMBL7470544 | 0.73 | MMP2 (0.33) | CYP1A2HIF1A | |
| SCHEMBL7024529 | 0.71 | KMT2A (0.33) | KMT2ABRD4CYP1A2HIF1A | |
| SCHEMBL8492515 | 0.69 | KMT2A (0.34) | KMT2ABRD4CYP1A2HIF1AGAA | |
| SCHEMBL5896745 | 0.68 | CYP1A2 (0.38) | KMT2ABRD4CYP1A2HIF1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162979-A1 | Substituted sulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-08-28 | — | — | US | disclosed |
| US-6441195-B1 | 2-ALKOXYCARBONYL-3-SULPHONAMIDE, SULPHONYL ISOCYANATE OR SULPHONYL ISOTHIOCYANATE-THIOPHENES; PRE- OR POSTEMERGENCE HERBICIDES; EFFICIENCY | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-27 | — | — | US | disclosed |
| US-6180567-B1 | REACTING 2-ALKOXYCARBONYL-BENZENESULFONAMIDE DERIVATIVE WITH 1,2,4-(1H)TRIAZOLE-5-(THI)ONE DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-30 | — | — | US | disclosed |
| US-3946111-A | ANALYGESICS | SHARPS ASSOCIATES (US) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162979-A1 | Substituted sulphonylamino(thio)carbonyl compounds | CBR3, CTH, CBR1 | KMT2A 2161/4885BRD4 2432/4885CYP1A2 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.