Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 18/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021927 | 0.89 | LTB4R (0.66) | LTB4R | |
| SCHEMBL7022921 | 0.88 | LTB4R (0.55) | LTB4R | |
| SCHEMBL7030559 | 0.82 | LTB4R (0.79) | LTB4R | |
| SCHEMBL8075663 | 0.75 | LTB4R (0.46) | LTB4R | |
| SCHEMBL8080183 | 0.73 | LTB4R (0.48) | LTB4R | |
| SCHEMBL8075079 | 0.73 | LTB4R (0.49) | LTB4R | |
| SCHEMBL7023912 | 0.72 | LTB4R (0.71) | LTB4R | |
| SCHEMBL8080568 | 0.71 | LTB4R (0.44) | LTB4R | |
| SCHEMBL7020057 | 0.70 | LTB4R (1.00) | LTB4R | |
| SCHEMBL7020052 | 0.70 | LTB4R (1.00) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649412-B1 | PHARMACEUTICAL PYRIDINE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2003-01-15 | — | — | EP | claimed |