Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.50 |
| ▸ | CTSL | P07711 | 7/20 | 0.50 |
| ▸ | CTSS | P25774 | 7/20 | 0.50 |
| ▸ | METAP2 | P50579 | 7/20 | 0.49 |
| ▸ | METAP1 | P53582 | 5/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363047 | 0.81 | CTSL (0.66) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7361168 | 0.81 | CTSL (0.66) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7033781 | 0.80 | CTSK (0.46) | CTSKCTSLCTSSMETAP2METAP1 | |
| SCHEMBL5934957 | 0.77 | CTSK (0.51) | CTSKCTSLCTSSMETAP2CTSB | |
| SCHEMBL5934599 | 0.77 | CTSK (0.51) | CTSKCTSLCTSSMETAP2CTSB | |
| SCHEMBL5934736 | 0.76 | CTSL (0.48) | CTSKCTSLCTSSMETAP2CTSB | |
| SCHEMBL7438845 | 0.74 | CTSL (0.57) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5934622 | 0.74 | CTSL (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5934617 | 0.74 | CTSL (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5934815 | 0.73 | CTSK (0.65) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929571-B1 | 4-SUBSTITUTED-3-(2-AMINO-2-CYCLOALKYL METHYL)-ACETAMIDO AZETIDIN-2-ONE DERIVATIVES AS CYSTEINE PROTEINASE REGULATORS | NAEJA PHARMACEUTICAL INC (CA) | 2003-02-26 | — | — | EP | disclosed |
| US-6034077-A | BONE DISORDERS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2000-03-07 | — | — | US | disclosed |
| WO-1999048911-A1 | MONOBACTAM ENZYME INHIBITORS | NAEJA PHARMACEUTICAL INC. (GB) | 1999-09-30 | — | — | WO | disclosed |
| EP-0929571-A1 | 4-SUBSTITUTED-3-(2-AMINO-2-CYCLOALKYL METHYL)-ACETAMIDO AZETIDIN-2-ONE DERIVATIVES AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (CA) | 1999-07-21 | — | — | EP | disclosed |
| US-5916887-A | TREATMENT OF ARTHRITIS, INFLAMMATION, ALZHEIMER'S DISEASE | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 1999-06-29 | — | — | US | disclosed |
| WO-1998012210-A1 | 4-SUBSTITUTED-3-(2-AMINO-2-CYCLOALKYL METHYL)-ACETAMIDO AZETIDIN-2-ONE DERIVATIVES AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (US) | 1998-03-26 | — | — | WO | disclosed |