⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10425067 | 0.93 | ALDH1A1 (0.54) | — | |
| SCHEMBL2476610 | 0.85 | — | — | |
| SCHEMBL29187635 | 0.80 | ALDH1A1 (0.68) | — | |
| SCHEMBL8988944 | 0.80 | ALDH1A1 (0.43) | — | |
| SCHEMBL13614263 | 0.79 | ALDH1A1 (0.52) | — | |
| SCHEMBL9502772 | 0.79 | ALDH1A1 (0.65) | — | |
| SCHEMBL6120423 | 0.78 | — | — | |
| SCHEMBL5165613 | 0.78 | — | — | |
| SCHEMBL100978 | 0.78 | — | — | |
| SCHEMBL159577 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135045-A1 | Glycoprotein IIb/IIIa antagonists | FISHER MATTHEW J (US) | 2003-07-17 | — | — | US | disclosed |
| US-20030130342-A1 | Glycoprotein llb/llla antagonists | FISHER MATTHEW J (US) | 2003-07-10 | — | — | US | disclosed |
| US-6472405-B1 | Glycoprotein IIB/IIIA antagonists | ELI LILLY AND COMPANY | 2002-10-29 | — | — | US | disclosed |
| EP-0635492-B1 | Glycoprotein IIb/IIIa antagonists | LILLY CO ELI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-6448269-B1 | SUCH AS 6-(N-(4-(AMINOIMINOMETHYL)BENZOYL)AMINO)-3,4-DIHYDRO-4,4-DIMETHYL-2H-1 -BENZOPYRAN-2-YL)ACETIC ACID; INHIBITING PLATELET AGGREGATION OR FIBRINOGEN BINDING OR PREVENTING THROMBOSIS | ELI LILLY AND COMPANY | 2002-09-10 | — | — | US | disclosed |
| US-6137002-A | USEFUL FOR PREVENTION OF THROMBOSIS; FOR TREATING ATHEROSCLEROSIS AND ARTERIOSCLEROSIS, ACUTE MYOCARDIAL INFARCTION, CHRONIC STABLE ANGINA, UNSTABLE ANGINA, TRANSIENT ISCHEMIC ATTACKS AND STROKES, PERIPHERAL VASCULAR DISEASE, | ELI LILLY AND COMPANY (US) | 2000-10-24 | — | — | US | disclosed |
| US-6020362-A | ANTICOAGULANTS | ELI LILLY AND COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0804431-A4 | GLYCOPROTEIN IIb/IIIa ANTAGONISTS | LILLY CO ELI (US) | 1998-04-29 | — | — | EP | disclosed |
| CN-1037841-C | Process for preparing substituted 4-phenyl-4-piperidinecarboxamide having local anaesthetic and analgesic effect | ASTRA CO (SE) | 1998-03-25 | — | — | CN | disclosed |
| US-5731324-A | Glycoprotein IIb/IIIa antagonists | ELI LILLY AND COMPANY (US) | 1998-03-24 | — | — | US | disclosed |
| EP-0804431-A1 | GLYCOPROTEIN IIb/IIIa ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-11-05 | — | — | EP | disclosed |
| US-5618843-A | INHIBIT PLATELET AGGREGATION | ELI LILLY AND COMPANY (US) | 1997-04-08 | — | — | US | disclosed |
| WO-1996022288-A1 | GLYCOPROTEIN IIb/IIIa ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |
| EP-0635492-A1 | Glycoprotein IIb/IIIa antagonists | ELI LILLY AND COMPANY (US) | 1995-01-25 | — | — | EP | disclosed |
| CN-1053605-A | Preparation method with new replacement 4-phenyl-4-piperidyl urea of toponarcosis and analgesic effect | ASTRA AB (SE) | 1991-08-07 | — | — | CN | disclosed |
| EP-0189774-B1 | PROCESS FOR PRODUCTION OF N,N-DISUBSTITUTED CARBOXYLIC ACID AMIDES | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1989-04-12 | — | — | EP | disclosed |
| EP-0189774-A1 | Process for production of N,N-disubstituted carboxylic acid amides | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | disclosed |